I would think it would greatly depend on the auto strain. Some of the old school autos like Lowryder bloom so darn quick & furiously, you really have no chance to try any sensible cropping. Their vegetative state is usually no more than 3 weeks, so by trimming you'll significantly reduce your harvest - IMHO.
I'd think it would be best to try LST with autos, that way you can bush em' out without cutting anything off.
But try a test grow, do a journal. I think it would be cool to see.