Be sure to take OMEGA 3 fatty acids from either Fish oil, flax seed oil, or hemp seed oil.
Here is a post from Granny storm:
“Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions.”
The corollaries of the obesity epidemic that plagues developed societies are malnutrition and resulting biochemical imbalances. Low levels of essential n-3 polyunsaturated fatty acids (n-3 PUFAs) have been linked to neuropsychiatric diseases, but the underlying synaptic alterations are mostly unknown. We found that lifelong n-3 PUFAs dietary insufficiency specifically ablates long-term synaptic depression mediated by endocannabinoids in the prelimbic prefrontal cortex and accumbens. In n-3-deficient mice, presynaptic cannabinoid CB(1) receptors (CB(1)Rs) normally responding to endocannabinoids were uncoupled from their effector G(i/o) proteins. Finally, the dietary-induced reduction of CB(1)R functions in mood-controlling structures was associated with impaired emotional behavior. These findings identify a plausible synaptic substrate for the behavioral alterations caused by the n-3 PUFAs deficiency that is often observed in western diets.
Granny’s (irreverent) translation and some implications-
"The US diet sucks big time! We are fat, undernourished and crazy because of it. We get WAY too much Omega 6, and not enough Omega 3. Not getting enough Omega 3 can make you a bit crazy because without it, the CB1 cannabinoid receptors on your brain cells can be deformed or broken! Our low Omega 3 diet is making us sick and crazy!"
Now, since the Omega 3-starved CB1 receptors are not working right, does this also mean that people, who have been deficient in Omega 3 for a while, are missing out on the full medical benefits- and the maximum high? Seems reasonable!
The two most popular forms of Omega 3 supplements are fish oils, and flax seed oil. Fish oil may be contaminated with mercury- so many people prefer to use flax seed oil. Pregnant women are often advised to use flax seed oil.
But there is another plant whose seeds are an even better source of Omega 3……….hemp! (3) The very thing we need to make our CB receptors work at their best, is found in the hemp plant! Cannabis buds are the source of the cannabinoids that we need to heal ourselves AND the oil from the seeds is the source of the Omega 3 we need for our receptors to do their jobs properly!
Some of you by now are thinking “Well, I’m up the creek! Never took a fish oil capsule in my life, I hate fish, never even seen hemp seed oil, and I dig KFC! My poor old CB receptors must be deformed as heck, and I’ll never get them working right! Bye-bye, maximum high!”
Well, guess what? Marijuana might cause new cell growth in the brain! (4) One of the many cannabinoid functions is making new brain cells! So if you were getting the Omega 3s you need, it would seem logical that the newly formed brain cells would be normal and healthy! Omega 3 might just be as good for your “head”, as it is for your heart!
But will just popping a few fish or hemp oil caps get you higher? Not likely, but if you keep it up, in time, those neurons with the defective CB1 receptors should be replaced with healthier ones. More importantly, for medical users, this may make the difference between health and sickness!
Properly functioning CB1 receptors are necessary both for the healing, and the high!