Few questions for my next grow

I just had a few questions about pollinating.
Is it ok to grow several different female strains in one area, and grow different male strains in another, and pollinate each different female with a different male pollin and expect that whichever strain i chose to pollinate is going to be infact that strain, considering im growing all the females in the same room? Because im thinking since they will be so close together then more than likely all the pollin will eventually make its way to all the plants, making them all crazy random mix strains.
Also, is it possible to pollinate an auto strain with a regular strain and expect auto seeds?

To help reduce cross-contamination, you can use plastic garbage bags while applying the pollen over a selected branch so that its no nearley as airbourne.

Thus less accidental pollination will occur, leaving more of you plants pollinated only by the pollen you wanted.

Sorry, not sure on the autoseed question... hope that helped!