under 24/0 and 18/6 the plants will eventually reach maturity and exhibit their sex. At that time they are ready for flowering and are begging you to swich to 12/12. However, in most cases the plants won't exhibit their sex until several weeks into the flowering stage and it's your discretion when you want to do this (i.e. they are a size you are comfortable with, have a good number of nodal growth, etc...) Many people on this site seem to switch to 12/12 after 1 month of veg. If you're like me and aren't using HID lights then you'll want to hand on longer than that to get the most bang for your buck