Question of prefrence: when should humidity dome come off?

Just out of curiousity I've seen varying opinions on when the humidity dome should come off, as well as should you ween seedlings out of the humidity dome, Feel free to post your opinion, b/c im curious who has gotten what results. So some say you should wait untill the roots have actually grown out of the rockwool, while other think immeditatly after sprout you should either start weening or take off the humidity dome. What do yall do?
Thanks,
Daxfool

I take seedlings out as soon as the first set of REAL leaves develop, and start a fan blowing on them to make their stalks strong (you really don't NEED to have seedlings under a dome, but I'm sure there are advantages). Clones I leave in until roots develop (because they need the humidity, they have no roots and must drink through their leaves).