I wouldnt use it unless you are really stuck. The fish actually benifit from the sodium bi-phosphate. It is also used as a bowel prep laxative if there is any one whos day you want to ruin, Gives EXPLOSIVE diarehea in about 20 mins.
I use nitric acid for PH down. 2 drops is enough for my 45 gallon rez to go from 5.4 to 5.7 at 1200ppm. My old natural down said it contained nitric acid so I went and bought a liter.