dstroy
Well-Known Member
Let me see if I can get access to the journals they published in.
THCP and CBDP - "new" compounds
- Thread starter dstroy
- Start date
Let me see if I can get access to the journals they published in.
Yes they are still looking for a single drug solution that will work better than growing and being dependent upon the entourage effect. Medicinal chemists gotta chem.
dstroy
Well-Known Member
I haven't been able to read everything yet but they were cataloguing compounds in one of their governments "medicinial" strains and found it. It hasn't been individually tested for efficacy or potency in humans.
cannabineer
Ursus marijanus
Oh absolutely. We provide the inestimable service of taking a good, efficacious natural mixture and refining or reworking it into a potent, dangerous entity that can then be trademarked and turned into a gravy train. And what benefits medicine is good for all humankind.
It's also because multivariate analysis of the entourage effect is virtually impossible and growing consistent cannabinoid content is next to impossible
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cannabineer
Ursus marijanus
It is a naturally occurring molecule. "Isolated" is the tell, not "prepared".
And yes, a higher binding constant to the receptor = more potent molecule.
Potency is often used to imply efficacy. The two are unrelated.
cannabineer
Ursus marijanus
Gotta amend this.
The compound was originally prepared (synthetic) and described by Adams et al. almost 80 years ago.
These researchers have found it in natural Cannabis.
Tetrahydrocannabiphorol is different from THC by having a heptyl (straight 7-carbon chain) group where THC has a pentyl (5-carbon) group.
ebcrew
Well-Known Member
So from what I'm reading it seems it's not naturally occurring. I could be reading wrong,
"In the newly discovered THCP molecule, the researchers found that a critical side chain in the molecule’s structure is elongated, with seven links. In comparison, regular THC has five links. To provide further context, naturally occurring cannabinoids with more than five links in this side chain have not yet been detected in cannabis. "
"In the newly discovered THCP molecule, the researchers found that a critical side chain in the molecule’s structure is elongated, with seven links. In comparison, regular THC has five links. To provide further context, naturally occurring cannabinoids with more than five links in this side chain have not yet been detected in cannabis. "
cannabineer
Ursus marijanus
No; these researchers isolated it from a plant extract.
This is one of those cool cases where a compound originally lab-made turns up in nature.
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