I buck the trend here as an older grower told me, I defoliate at 23 days and usually near 43. Always removing fan leaves that are attached to main branch or blocking bud sites, not a fan that is directly attach to a bud site. I do this in veg too, as I train my plants to deal with this and they never have an issue either.
I am no botanic expert but I know plants can transfer food energy throughout the plant, except for a few nutrients. I grow in DWC so the nutes are ALWAYS available to the plant, and I am sure my buds are equal or better then anyone's for size/girth, smell/aroma or just flower time for doing it this way (granted same conditions light, strain, medium). Hell I did it myself, non-defoliating and defoliating, the plants always finished the same time but the defoliated plants had the bigger, better looking buds by far. It facilitates more air flow, light penetration and room for the plants I have never seen a down side or side effect from doing this.
I mean sometimes I think I over do it, and the plants love it. It is sad that people want to believe half-truths, mis-information without even trying it for themselves. I sacrificed my first plant after talking to this gentleman over 3 years ago, and it is the ONLY way I would ever grow. Not knocking the people who don't touch their plants, it's just like the argument flush or don't flush everyone has their opinion, sad thing is that most people just believe someone else because of ignorance and not seeing the effects for themselves.
Steps off soapbox...