For my first grow I used synthetic fertilizers (CANNA Tera line) and while the buds were good, the flavor wasn't all that (especially disappointing for Bubblegum- a typically fruity strain) and the smoke was a bit harsh and didn't stay lit.
Also, I noticed that with chems the plants were a lot more fussy and had a lot of micronutrient deficiencies.
I've switched to organic fertilizers for my 2nd grow (BioBizz) and my plants and I couldn't be happier!
The yield might be slightly less (even that's debatable) but the quality more than makes up for it.
Do the switch!