oxycontin ER

[canndo]

he doesn't have the new ones....
but it's still really easy, just the membrane isnt on the outside to allow opening of the pill, now there are spheroids. cool so you can sprinkle the powder in shit...but still, just dissolve the matrix

Not any more. Nor is the coating the slowing factor. The active chemical is placed in a complex that dissolves very slowly. It will conglomerate into a sticky slimy mess. Cutting it in half does nothing at all, chewing it is no better and the crap sticks to your teeth. The matrix takes days to dissolve in water as it was meant for the digestive tract.

 

[BarnBuster]

Not any more. Nor is the coating the slowing factor. The active chemical is placed in a complex that dissolves very slowly. It will conglomerate into a sticky slimy mess. Cutting it in half does nothing at all, chewing it is no better and the crap sticks to your teeth. The matrix takes days to dissolve in water as it was meant for the digestive tract.

You have given out too much Reputation in the last 24 hours, try again later.

 

[tyedyed60]

Thanks for all the feedback, but I think this is just another failed attempt at getting off these damn fentanyl patches. So I guess I will just throw them out & go back to hoping the damn patches will stick without the use of duct tape

 

[canndo]

Find a place that is broad enough and does not move much. Be sure you wash the site well, some manufacturers do a better job than others.

 

[the church man]

Tincture of Benzoin can help the adhesive to stick longer; but make sure you use the compound and not the plain.

Good luck to you.

 

[pSi007]

Dude he's going from fent to ER OC... that's like going from dabs to mid-grade weed. Opiates aren't that dangerous health-wise imo.

As an EMT for 7 years, I have personally seen the effect of prescribed opiate drug use and the dangers involved. I have seen maybe 100 overdoses on prescription drugs(80% = hydro/oxy), maybe 5 for heroin, 2 for cocaine, maybe 20 for tranqs.. Don't tell me that destroying the timed release is not an issue or that Oxycontin is like "mid-grade" weed..

I will look at you and personally tell you in public, BULLSHIT!


Canno, "Extended release" is different than "Controlled release". Oxy-"contin" where "contin" means continuous release..

tyedyed60, tell your doctor the oxy-ER are doing very little and ask for a "Roxicontin".. they are usually much less mg and they are not timed release. 15mg of Roxi will hit you in full effect in about 30-45 min and does not have Tylenol or other liver-killers, so, yes, they are safer when used by the book.

http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=000dde4b-1d94-442f-94c0-26e283e04d88

OxyContin TABLETS ARE TO BE SWALLOWED WHOLE AND ARE NOT TO BE BROKEN, CHEWED, OR CRUSHED. TAKING BROKEN, CHEWED, OR CRUSHED OxyContin TABLETS LEADS TO RAPID RELEASE AND ABSORPTION OF A POTENTIALLY FATAL DOSE OF OXYCODONE.

 

[pSi007]

my Dr. wanted me to try the oxy 40's with the norcos to see if it would work .. I took 6 a once & there was NO relief at all so I had to take aa shit load more norcos to compensate.

you are playing a dangerous dance with the devil, my friend. 240mg of oxy with the timed-release removed will kill most humans if ingested rapidly. Some people scratch the coating off the oxys and shoot or snort them, far too many deaths.. Maybe you should try some different forms of professional help before it's too late.

my advice..

 

[canndo]

As an EMT for 7 years, I have personally seen the effect of prescribed opiate drug use and the dangers involved. I have seen maybe 100 overdoses on prescription drugs(80% = hydro/oxy), maybe 5 for heroin, 2 for cocaine, maybe 20 for tranqs.. Don't tell me that destroying the timed release is not an issue or that Oxycontin is like "mid-grade" weed..

I will look at you and personally tell you in public, BULLSHIT!


Canno, "Extended release" is different than "Controlled release". Oxy-"contin" where "contin" means continuous release..

tyedyed60, tell your doctor the oxy-ER are doing very little and ask for a "Roxicontin".. they are usually much less mg and they are not timed release. 15mg of Roxi will hit you in full effect in about 30-45 min and does not have Tylenol or other liver-killers, so, yes, they are safer when used by the book.

http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=000dde4b-1d94-442f-94c0-26e283e04d88

Please explain extended release as opposed to "controlled release and "continuous" release. My understanding is that there is some early work on varying blood plasma levels through changing release patterns in pills, establishing high levels as early as possible then perhaps changing that pattern as it may suit the patient's needs in a pre defined way.

But we know that there is a curve in plasma levels and that they begin to taper, depending upon the persons metabolism, his food intake etc, after what? 4 or 5 hours? Now extended release to my understanding simply keeps the plasma levels at a certain level by replenishing what has been metabolized. The pill might work for what? 8? 12 hours? Fine. Now how is that any different than "controlled release" I.E. keeping the entire dose from being absorbed at the same time, or continuous release which seems to mean the same thing.

I do not doubt that you have encountered more pharma opiates given the larger number of pharma users and the notion that if a doctor prescribes it, or if it is a pill, it must be somehow safer. I believe that Skuxx was responding to the fact that the OP was far from a virgin user, having been taking a pain medication that is usually only prescribed to patients who have established opioid tolerance. Taking this into account with the fact that we know the OP has 40 mg pills, it is most unlikely that he is liable to have a problem with a pill who's matrix was defeated. Furthermore notice I did suggest that it be titrated in some way just to be on the safe side.

 

[canndo]

you are playing a dangerous dance with the devil, my friend. 240mg of oxy with the timed-release removed will kill most humans if ingested rapidly. Some people scratch the coating off the oxys and shoot or snort them, far too many deaths.. Maybe you should try some different forms of professional help before it's too late.

my advice..

I concur with pSi007. While the matrix of the 40's cause it to conglomerate and so the surface area of that conglomeration will keep the absorption levels down a bit, there have been reported problems with the release, a phenomenon called, if I recall, "dose dumping" can occur, especially if you drink alcohol and sometimes other foods or liquids. this dose dumping might not do more than put you into a nod with 40 mg but even with a tolerance, you might have a problem with multiple pills at once. Recall as well that there is a residual level of fentanyl in your skin if you recently had a patch on. Lastly, scratching the coating from the new pills
will do nothing to the slow release properties of the modern Oxycontin pill.

 

[qwizoking]

I was speaking on the extended release. and the deterx patent formulations..of which I'm very familiar

 

[pSi007]

Please explain extended release as opposed to "controlled release and "continuous" release. My understanding is that there is some early work on varying blood plasma levels through changing release patterns in pills, establishing high levels as early as possible then perhaps changing that pattern as it may suit the patient's needs in a pre defined way.

But we know that there is a curve in plasma levels and that they begin to taper, depending upon the persons metabolism, his food intake etc, after what? 4 or 5 hours? Now extended release to my understanding simply keeps the plasma levels at a certain level by replenishing what has been metabolized. The pill might work for what? 8? 12 hours? Fine. Now how is that any different than "controlled release" I.E. keeping the entire dose from being absorbed at the same time, or continuous release which seems to mean the same thing.

I do not doubt that you have encountered more pharma opiates given the larger number of pharma users and the notion that if a doctor prescribes it, or if it is a pill, it must be somehow safer. I believe that Skuxx was responding to the fact that the OP was far from a virgin user, having been taking a pain medication that is usually only prescribed to patients who have established opioid tolerance. Taking this into account with the fact that we know the OP has 40 mg pills, it is most unlikely that he is liable to have a problem with a pill who's matrix was defeated. Furthermore notice I did suggest that it be titrated in some way just to be on the safe side.

OxyContin (oxycodone hydrochloride controlled-release), all are "continuous controlled" release. They do this by creating multiple layers of active and inactive ingredients which dissolve at different rates. Think of Oxycontin as Damascus steel, where there are layers of soft in between layers of hard. Chopping the pill will limit the continual release but it will still try to dissolve in layers. crushing the pill after removing the outer protective layer will allow the "instant and full effect", remember, 40mg with "instant and full effect" is dangerous and very possibly lethal to humans.

OxyER means it has more layers and a higher dosage. Regular Oxy @ 40mg is stronger than the ER version.

I was speaking on the extended release. and the deterx patent formulations..of which I'm very familiar

Canton, MA-— February 12, 2013—Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, today announced that it has received Notice of Allowance from the U.S. Patent and Trademark Office (USPTO) for its patent application "Abuse-Deterrent Drug Formulation" US Patent Application Number 12/823,628. The Notice of Allowance is the USPTO’s official communication that the Company’s application has successfully completed examination and that a patent will be issued. This will be the third issued patent related to the DETERx[SUP]®[/SUP] drug delivery technology.

The allowed patent claims cover the Company’s lead development program Oxycodone DETERx[SUP]®[/SUP](COL-003), a tamper-resistant, extended-release oxycodone product utilizing its proprietary DETERx[SUP]®[/SUP]technology. The Oxycodone DETERx[SUP]®[/SUP] formulation was specifically designed to provide and preserve extended release of the active ingredient following the most common methods of product tampering employed by drug abusers (e.g., crushing, chewing, heating for IV injection, etc.). The product is currently in the final stage of clinical development and has been designated Fast Track Status by the FDA due to its potential to address the problem of prescription drug abuse, a major public health issue in the U.S.

http://www.collegiumpharma.com/press-releases/88-january-17-2013-collegium-pharmaceutical-announces-relocation-to-massachusetts




Tyedye, ask your doctor about Roxicontin if you have immediate pain which needs strong medication. Dont try to turn Oxycontin ER into Roxicontin.

 

[pSi007]

I cant edit my post.. ok.. So it is really amazing how these patents are working for these multi-billion $$ industry. I, myself, would like to chop and snort an Oxy like a champ but I never have nor have I mustard the reason.. The oxys work by using a dissolving "time-release", this will cause the oxy to dissolve and be absorbed over a long period of time.

We dont have anything that is a true, "opiate blocker" other than narcan and believe me, if you are used to taking opiates, the Narcan would feel like nails in your body.. So, it's not a plasma blocker.. These drug companies are reluctant to release the full information but I assume the federal patent is out there. ok, I think it is an oral ingestion blocker which causes the Oxy to become inert while it is being digested. After these, "time-release" parts dissolve, the oxy can then be absorbed.


you want to defeat the oral absorption of Oxy? Try suppository and dont blame me if you OD. lol.. I am warning you before you try it on your own. (snorting gets absorbed via nasal nerves and 80% oral ingested, "nasal runs") IV and Up-The-Arse would defeat the true timed-release..

remember, each 40mg of "timed release" is like 5-10mg of instant. Seriously, ask your Doctor about a "RoxiContine".

 

[pSi007]

billion dollar industry..


edit.. you can also try soaking the beads in a few mL of lemon juice, give it a few hours, steel strainer, dry, drink, drop, do w/e.. that should get it out and reproduce the elements of the digestive system and get that purple spike back from Deterx

edit: if that does not work, try lemon juice with dissolved chloride(table salt), and epsom salt (sulfur). Dont shoot the heavy salts but in the nose, mouth, or butt should be fine.. hahaha.. medicine.. I <3 it!