Olive Drab Green
Well-Known Member
You lost me, Bud.
Random Jibber Jabber Thread
- Thread starter Trolling
- Start date
abe supercro
Well-Known Member
And blood shot eyes.
Olive Drab Green
Well-Known Member
I'd imagine you could be right, Abe. Some people get really low BP and Bradycardia and pass out if they stand up too fast.
Olive Drab Green
Well-Known Member
@curious2garden Are you referring to Factor IX? I suppose if you had Christmas Factor Deficiency (a la Stephen Christmas) , were smoking, and you got cut, or had the clotting mutation, then maybe it's contraindicated.
++ rep
Thank you, you got my point precisely, you are very clever because I am very impaired and I so appreciate the assist.
I'm saying if you have a weakness, say cardiac arrythmias and smoke a strong sativa pot CAN kill you. OOPS and it has....... it's just not what is typed on the death cert. But it will be attributed to your broke ass heart not the pot.
Olive Drab Green
Well-Known Member
I suppose. Probably should stick to indy if you're a broke dick.
Back when I grew up mexi-brick was the perfect weed. There was no ceiling and you dialed in your high by puffs. So different from today.
ovo
Well-Known Member
a compassionate term for someone with health problems. we really are all enlisted whether we know it or not.
tangerinegreen555
Well-Known Member
And we always wanted something a little bit better...
Olive Drab Green
Well-Known Member
eye exaggerate
Well-Known Member
tyler.durden
Well-Known Member
This really made me smile...
qwizoking
Well-Known Member
its early...and im not typing all this, so fprgive the choppy structure. yiu get the idea though ...or should...
i hope
and yes i know posting things like this on a weed forum leaves people with a bad taste
essentially what im saying is hitting so many receptors in the brain CAN NOT be without side effect. plain and simple. luckily we gain tolerance quickly and its not very powerful in regards to agonism.
ok point #1
cerebellar infarction was confirmed by biopsy (1 case) or necropsy (2 cases)... Brainstem compromise caused by cerebellar and cerebral edema led to death in 2 fatal cases."
Apr. 4, 2004 - Thomas Geller, MD
Cannabis is generally considered to be a drug with very low toxicity. In this paper, we report six cases where recent cannabis intake was associated with sudden and unexpected death. An acute cardiovascular event was the probable cause of death. In all cases, cannabis intake was documented by blood analysis...
Dec. 27, 2001 - Liliana Bachs, MD
fda says contributed to 279 deaths from 97-2005.
in perfectly healthy indivisuals I wouldn't worry. fda says only the primary cause in 4 cases and was on mostly thc/marinol. but if your unhealthy, biggest issues are the heart, neural excitement, loss of blood flow to extremities, pancreas and liver problems....its not completely benign
point #2
thc used to be widely known as a hallucinogen, depressant AND stimulant.
this mainly occurs in new users. once you gain a tolerance, pop site density lowers to a level where thc- a partial agonist can take up more space than it activates causing antagonism instead of agonism...essentially . in new users it can act like the much more potent full agonist jwh018 . seizures, loss of coordination etc effects we are familiar with. but even afterprolonged tolerance break, this site density does not return to complete baseline. heavy opiate users often say the same thing, just throwing examples
if your personal site density is altered, say your sick or depressed which can change 5ht (serotonin) this makes a difference. everyone is a weee bit different
and yes sadly enough ive personally seen deaths caused by cannabis.
looking at the structure of thc we can estimate(with accuracy) and through testing know what sites it will hit and how effectively. roughly 20 are being hit when smoking cannabis....think about that
it does alter heart rate, blood sugar, blood flow to extremities, ion blocking properties and vision (photophobia) as well as other inherent affects, alters hormones, and altering a system in your brain has ever only been beneficial if "off" to begin with. Look into sigma 1, 5ht2a, serotonin in general, dopamine, gabba,nmda cb1,2,"3""4" etc.. we know it hits these sites and more, we know what these sites do when hit.
for example. (published in 2014)
Studies in humans have indicated that abuse of smoked cannabis can promote psychosis and even circumstantially precipitate symptoms of schizophrenia, although the latter appears to require a prior vulnerability in the individual. It is possible that cannabinoids provoke psychosis/schizophrenia reflecting a mechanism common to neuroprotection: the reduction of NMDAR activity. Cannabinoids are proposed to produce such effect by reducing the pre-synaptic release of glutamate or interfering with post-synaptic NMDAR-regulated signaling pathways. The efficacy of such control requires the endocannabinoid system to apply its negative influence in a manner that is proportional to the strength of NMDAR signaling. Thus, cannabinoids acting at the wrong time or exerting an inappropriate influence on their receptors may cause NMDAR hypofunction. The purpose of the present review is to draw the attention of the reader to the newly described functional and physical CB1-NMDAR association
i see this alot in conducted studies..isit debilitating..no, some people may not even notice, but delusional thoughts maybe feelings of grandeur etc are quite common
i know some of you remember
music tripping you out or dodging objects on your tv, even just some effects like spinning when you close your eyes, loosing balance, memory loss etc this
mainly occurs in new users. Some you can still get especially when combined with other substances say alcohol or dxm and to a degree...
Be careful with "nerve symptoms" and thc. Idk what you meant but whether anxiety or nervous pain it can be detrimental especially in low tolerance patients or those who jump dosage. That thc will kick again, these bi and triphasic properties make cannabis difficult to use effectively in a traditional medical setting
I simply couldn't smoke more than a couple hits after surgeries and nerve damage would cause buzzing then intense pain
another i briefly mentioned
Everyone i know smoking excess of 3-4oz a week has mild photophobia. It is the only statistically known side effect via bioaccumulation. It subsides in about a month, 2 months and mostly resolved but will quickly return...atleast in the cases ive seen. Smoking resin seems to drastically hasten progression
and i forgot my points
look weed is great. but lets not romanticize the plant and view it as some miracle herb. thats not helping us any, just makes us look like delusional morons
yes i want it legal too
i hope
and yes i know posting things like this on a weed forum leaves people with a bad taste
essentially what im saying is hitting so many receptors in the brain CAN NOT be without side effect. plain and simple. luckily we gain tolerance quickly and its not very powerful in regards to agonism.
ok point #1
cerebellar infarction was confirmed by biopsy (1 case) or necropsy (2 cases)... Brainstem compromise caused by cerebellar and cerebral edema led to death in 2 fatal cases."
Apr. 4, 2004 - Thomas Geller, MD
Cannabis is generally considered to be a drug with very low toxicity. In this paper, we report six cases where recent cannabis intake was associated with sudden and unexpected death. An acute cardiovascular event was the probable cause of death. In all cases, cannabis intake was documented by blood analysis...
Dec. 27, 2001 - Liliana Bachs, MD
fda says contributed to 279 deaths from 97-2005.
in perfectly healthy indivisuals I wouldn't worry. fda says only the primary cause in 4 cases and was on mostly thc/marinol. but if your unhealthy, biggest issues are the heart, neural excitement, loss of blood flow to extremities, pancreas and liver problems....its not completely benign
point #2
thc used to be widely known as a hallucinogen, depressant AND stimulant.
this mainly occurs in new users. once you gain a tolerance, pop site density lowers to a level where thc- a partial agonist can take up more space than it activates causing antagonism instead of agonism...essentially . in new users it can act like the much more potent full agonist jwh018 . seizures, loss of coordination etc effects we are familiar with. but even afterprolonged tolerance break, this site density does not return to complete baseline. heavy opiate users often say the same thing, just throwing examples
if your personal site density is altered, say your sick or depressed which can change 5ht (serotonin) this makes a difference. everyone is a weee bit different
and yes sadly enough ive personally seen deaths caused by cannabis.
looking at the structure of thc we can estimate(with accuracy) and through testing know what sites it will hit and how effectively. roughly 20 are being hit when smoking cannabis....think about that
it does alter heart rate, blood sugar, blood flow to extremities, ion blocking properties and vision (photophobia) as well as other inherent affects, alters hormones, and altering a system in your brain has ever only been beneficial if "off" to begin with. Look into sigma 1, 5ht2a, serotonin in general, dopamine, gabba,nmda cb1,2,"3""4" etc.. we know it hits these sites and more, we know what these sites do when hit.
for example. (published in 2014)
Studies in humans have indicated that abuse of smoked cannabis can promote psychosis and even circumstantially precipitate symptoms of schizophrenia, although the latter appears to require a prior vulnerability in the individual. It is possible that cannabinoids provoke psychosis/schizophrenia reflecting a mechanism common to neuroprotection: the reduction of NMDAR activity. Cannabinoids are proposed to produce such effect by reducing the pre-synaptic release of glutamate or interfering with post-synaptic NMDAR-regulated signaling pathways. The efficacy of such control requires the endocannabinoid system to apply its negative influence in a manner that is proportional to the strength of NMDAR signaling. Thus, cannabinoids acting at the wrong time or exerting an inappropriate influence on their receptors may cause NMDAR hypofunction. The purpose of the present review is to draw the attention of the reader to the newly described functional and physical CB1-NMDAR association
i see this alot in conducted studies..isit debilitating..no, some people may not even notice, but delusional thoughts maybe feelings of grandeur etc are quite common
i know some of you remember
music tripping you out or dodging objects on your tv, even just some effects like spinning when you close your eyes, loosing balance, memory loss etc this
mainly occurs in new users. Some you can still get especially when combined with other substances say alcohol or dxm and to a degree...
Be careful with "nerve symptoms" and thc. Idk what you meant but whether anxiety or nervous pain it can be detrimental especially in low tolerance patients or those who jump dosage. That thc will kick again, these bi and triphasic properties make cannabis difficult to use effectively in a traditional medical setting
I simply couldn't smoke more than a couple hits after surgeries and nerve damage would cause buzzing then intense pain
another i briefly mentioned
Everyone i know smoking excess of 3-4oz a week has mild photophobia. It is the only statistically known side effect via bioaccumulation. It subsides in about a month, 2 months and mostly resolved but will quickly return...atleast in the cases ive seen. Smoking resin seems to drastically hasten progression
and i forgot my points
look weed is great. but lets not romanticize the plant and view it as some miracle herb. thats not helping us any, just makes us look like delusional morons
yes i want it legal too
Last edited:
.Pinworm.
Well-Known Member
Last night was really fun, that's what I heard from almost everyone
I got a hand stamp but not a first hand account
I don't remember what booze I drank, I'm not sure what kind of drugs were done
Without any account can you count it as fun?
I don't remember what notes to play, I don't remember the words I sing
Was it a good show if you can't remember a thing?
Who sharpied 'slut' on my forehead?
How did this blood get on my shirt?
Was it aggravated assault if you're the only one who got hurt?
I might have met him on myspace, I think I went over to his place
Does it count as sex if you can't remember his face?
Was it a good time? What did we talk about?
Afternoon fades to blackout
.Pinworm.
Well-Known Member
maybe this is the right time for a supervised detox. just kidding, lets match some lines...its early...and im not typing all this, so fprgive the choppy structure. yiu get the idea though ...or should...
i hope
and yes i know posting things like this on a weed forum leaves people with a bad taste
essentially what im saying is hitting so many receptors in the brain CAN NOT be without side effect. plain and simple. luckily we gain tolerance quickly and its not very powerful in regards to agonism.
ok point #1
cerebellar infarction was confirmed by biopsy (1 case) or necropsy (2 cases)... Brainstem compromise caused by cerebellar and cerebral edema led to death in 2 fatal cases."
Apr. 4, 2004 - Thomas Geller, MD
Cannabis is generally considered to be a drug with very low toxicity. In this paper, we report six cases where recent cannabis intake was associated with sudden and unexpected death. An acute cardiovascular event was the probable cause of death. In all cases, cannabis intake was documented by blood analysis...
Dec. 27, 2001 - Liliana Bachs, MD
fda says contributed to 279 deaths from 97-2005.
in perfectly healthy indivisuals I wouldn't worry. fda says only the primary cause in 4 cases and was on mostly thc/marinol. but if your unhealthy, biggest issues are the heart, neural excitement, loss of blood flow to extremities, pancreas and liver problems....its not completely benign
point #2
thc used to be widely known as a hallucinogen, depressant AND stimulant.
this mainly occurs in new users. once you gain a tolerance, pop site density lowers to a level where thc- a partial agonist can take up more space than it activates causing antagonism instead of agonism...essentially . in new users it can act like the much more potent full agonist jwh018 . seizures, loss of coordination etc effects we are familiar with. but even afterprolonged tolerance break, this site density does not return to complete baseline. heavy opiate users often say the same thing, just throwing examples
if your personal site density is altered, say your sick or depressed which can change 5ht (serotonin) this makes a difference. everyone is a weee bit different
and yes sadly enough ive personally seen deaths caused by cannabis.
looking at the structure of thc we can estimate(with accuracy) and through testing know what sites it will hit and how effectively. roughly 20 are being hit when smoking cannabis....think about that
it does alter heart rate, blood sugar, blood flow to extremities, ion blocking properties and vision (photophobia) as well as other inherent affects, alters hormones, and altering a system in your brain has ever only been beneficial if "off" to begin with. Look into sigma 1, 5ht2a, serotonin in general, dopamine, gabba,nmda cb1,2,"3""4" etc.. we know it hits these sites and more, we know what these sites do when hit.
for example. (published in 2014)
Studies in humans have indicated that abuse of smoked cannabis can promote psychosis and even circumstantially precipitate symptoms of schizophrenia, although the latter appears to require a prior vulnerability in the individual. It is possible that cannabinoids provoke psychosis/schizophrenia reflecting a mechanism common to neuroprotection: the reduction of NMDAR activity. Cannabinoids are proposed to produce such effect by reducing the pre-synaptic release of glutamate or interfering with post-synaptic NMDAR-regulated signaling pathways. The efficacy of such control requires the endocannabinoid system to apply its negative influence in a manner that is proportional to the strength of NMDAR signaling. Thus, cannabinoids acting at the wrong time or exerting an inappropriate influence on their receptors may cause NMDAR hypofunction. The purpose of the present review is to draw the attention of the reader to the newly described functional and physical CB1-NMDAR association
i see this alot in conducted studies..isit debilitating..no, some people may not even notice, but delusional thoughts maybe feelings of grandeur etc are quite common
i know some of you remember
music tripping you out or dodging objects on your tv, even just some effects like spinning when you close your eyes, loosing balance, memory loss etc this
mainly occurs in new users. Some you can still get especially when combined with other substances say alcohol or dxm and to a degree...
Be careful with "nerve symptoms" and thc. Idk what you meant but whether anxiety or nervous pain it can be detrimental especially in low tolerance patients or those who jump dosage. That thc will kick again, these bi and triphasic properties make cannabis difficult to use effectively in a traditional medical setting
I simply couldn't smoke more than a couple hits after surgeries and nerve damage would cause buzzing then intense pain
another i briefly mentioned
Everyone i know smoking excess of 3-4oz a week has mild photophobia. It is the only statistically known side effect via bioaccumulation. It subsides in about a month, 2 months and mostly resolved but will quickly return...atleast in the cases ive seen. Smoking resin seems to drastically hasten progression
and i forgot my points
look weed is great. but lets not romanticize the plant and view it as some miracle herb. thats not helping us any, just makes us look like delusional morons
.Pinworm.
Well-Known Member
I bet i can do more pushups than you right now
evergreengardener
Well-Known Member
hey everyone been gone awhile car accident broke my shoulder able to use arm somewhat again so I can type again my grow suffered some but itll make it through had to veg about 3 weeks longer than i wanted as i couldnt change out my lights and hang filter but now on week 2 since flip alls looking well
.Pinworm.
Well-Known Member
Welcome back. That must of sucked.