Random Jibber Jabber Thread

Olive Drab Green

Olive Drab Green

Well-Known Member
evergreengardener said:
hey everyone been gone awhile car accident broke my shoulder able to use arm somewhat again so I can type again my grow suffered some but itll make it through had to veg about 3 weeks longer than i wanted as i couldnt change out my lights and hang filter but now on week 2 since flip alls looking well
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Hurray for near-death experiences! Welcome back, and Sláinte!
 
cannabineer

cannabineer

Ursus marijanus
Olive Drab Green said:
Cannabis has never caused a death. I understand that it does cause mild to moderate tachycardia, but they prescribe it to dying cancer patients. That's my take. Nothing really to back it up except statistics that show no one has died from marijuana.
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qwizoking said:
its early...and im not typing all this, so fprgive the choppy structure. yiu get the idea though ...or should...
i hope



and yes i know posting things like this on a weed forum leaves people with a bad taste ;)










essentially what im saying is hitting so many receptors in the brain CAN NOT be without side effect. plain and simple. luckily we gain tolerance quickly and its not very powerful in regards to agonism.

ok point #1

cerebellar infarction was confirmed by biopsy (1 case) or necropsy (2 cases)... Brainstem compromise caused by cerebellar and cerebral edema led to death in 2 fatal cases."
Apr. 4, 2004 - Thomas Geller, MD

Cannabis is generally considered to be a drug with very low toxicity. In this paper, we report six cases where recent cannabis intake was associated with sudden and unexpected death. An acute cardiovascular event was the probable cause of death. In all cases, cannabis intake was documented by blood analysis...
Dec. 27, 2001 - Liliana Bachs, MD


fda says contributed to 279 deaths from 97-2005.
in perfectly healthy indivisuals I wouldn't worry. fda says only the primary cause in 4 cases and was on mostly thc/marinol. but if your unhealthy, biggest issues are the heart, neural excitement, loss of blood flow to extremities, pancreas and liver problems....its not completely benign


point #2

thc used to be widely known as a hallucinogen, depressant AND stimulant.


this mainly occurs in new users. once you gain a tolerance, pop site density lowers to a level where thc- a partial agonist can take up more space than it activates causing antagonism instead of agonism...essentially . in new users it can act like the much more potent full agonist jwh018 . seizures, loss of coordination etc effects we are familiar with. but even afterprolonged tolerance break, this site density does not return to complete baseline. heavy opiate users often say the same thing, just throwing examples

if your personal site density is altered, say your sick or depressed which can change 5ht (serotonin) this makes a difference. everyone is a weee bit different

and yes sadly enough ive personally seen deaths caused by cannabis.

looking at the structure of thc we can estimate(with accuracy) and through testing know what sites it will hit and how effectively. roughly 20 are being hit when smoking cannabis....think about that



it does alter heart rate, blood sugar, blood flow to extremities, ion blocking properties and vision (photophobia) as well as other inherent affects, alters hormones, and altering a system in your brain has ever only been beneficial if "off" to begin with. Look into sigma 1, 5ht2a, serotonin in general, dopamine, gabba,nmda cb1,2,"3""4" etc.. we know it hits these sites and more, we know what these sites do when hit.


for example. (published in 2014)
Studies in humans have indicated that abuse of smoked cannabis can promote psychosis and even circumstantially precipitate symptoms of schizophrenia, although the latter appears to require a prior vulnerability in the individual. It is possible that cannabinoids provoke psychosis/schizophrenia reflecting a mechanism common to neuroprotection: the reduction of NMDAR activity. Cannabinoids are proposed to produce such effect by reducing the pre-synaptic release of glutamate or interfering with post-synaptic NMDAR-regulated signaling pathways. The efficacy of such control requires the endocannabinoid system to apply its negative influence in a manner that is proportional to the strength of NMDAR signaling. Thus, cannabinoids acting at the wrong time or exerting an inappropriate influence on their receptors may cause NMDAR hypofunction. The purpose of the present review is to draw the attention of the reader to the newly described functional and physical CB1-NMDAR association

i see this alot in conducted studies..isit debilitating..no, some people may not even notice, but delusional thoughts maybe feelings of grandeur etc are quite common




i know some of you remember
music tripping you out or dodging objects on your tv, even just some effects like spinning when you close your eyes, loosing balance, memory loss etc this
mainly occurs in new users. Some you can still get especially when combined with other substances say alcohol or dxm and to a degree...


Be careful with "nerve symptoms" and thc. Idk what you meant but whether anxiety or nervous pain it can be detrimental especially in low tolerance patients or those who jump dosage. That thc will kick again, these bi and triphasic properties make cannabis difficult to use effectively in a traditional medical setting
I simply couldn't smoke more than a couple hits after surgeries and nerve damage would cause buzzing then intense pain



another i briefly mentioned


Everyone i know smoking excess of 3-4oz a week has mild photophobia. It is the only statistically known side effect via bioaccumulation. It subsides in about a month, 2 months and mostly resolved but will quickly return...atleast in the cases ive seen. Smoking resin seems to drastically hasten progression




and i forgot my points







look weed is great. but lets not romanticize the plant and view it as some miracle herb. thats not helping us any, just makes us look like delusional morons
yes i want it legal too
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Plus rep, quizo. Impressive and it confirms what Annie and I think about the drug.

I pissed an instructor way off once when I observed that "a chemical is either useful ... or it's safe." And that is a fact of our related professions. Well done sir.
 
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