(CBRN) Chemical, Biological, Radiological & Nuclear

Drowning-Man · Jun 17, 2016

Thank God end of the day. Wanna hit this?

abe supercro · Jun 17, 2016

Drowning-Man said:
Thank God end of the day. Wanna hit this?
View attachment 3710865

thanks but im gonna vape a few turkey bags of volcano and finish that bbq

Drowning-Man · Jun 17, 2016

abe supercro said:
thanks but im gonna vape a few turkey bags of volcano and finish that bbq

Damn ima eat some yogurt

eye exaggerate · Jun 18, 2016

curious2garden said:
Wow, just wow! How is it possible you can type so many words with so little understanding of what you, yourself just wrote. In psychiatry, this type of verbalization is called echolalia.

I ear of dat before.

Finshaggy · Jun 18, 2016

Olive Drab Green said:
You're not talking other substances, you are saying that you are going to smoke. They will catch you. You will be fucked. I'm trying to seriously warn you.

Iwas talking other substances, then you brought up my Religion and the fact that I have grown Marijuana ect. And I went along with your line of discussion, but I was originally talking other substances, I can find the post for you.

Olive Drab Green · Jun 18, 2016

Finshaggy said:
Iwas talking other substances, then you brought up my Religion and the fact that I have grown Marijuana ect. And I went along with your line of discussion, but I was originally talking other substances, I can find the post for you.

You brought up your own religion. And so did someone else, telling you that won't fly, and I concurred. I'm trying to help you, not hinder you. You had said you are still going to smoke and try to feel out the cycles. If you don't want my advice, which I'm truly giving you from my heart, I won't waste my breath, man.

Finshaggy · Jun 18, 2016

I even ended it with "And you can get mail". I remember the post. And when I said "And you can get mail" it's because legal substances can just be sent in the mail.

Finshaggy · Jun 18, 2016

Olive Drab Green said:
There is nothing you can use. You sign a contract. It doesn't work the way you think it does. You're going to be telling them "You can't do that!" And they're going to show you that they can.

I have known people that used legal things in the military, again, they used to smoke K2 and stuff.

Olive Drab Green · Jun 18, 2016

Finshaggy said:
I have known people that used legal things in the military, again, they used to smoke K2 and stuff.

I did, myself, in '09. They check your barracks room. It's called "barracks inspection. That happens every month or two. The UCMJ is the military's bylaws and while Spice is legal in the civilian world, it is illegal in the military.

Finshaggy · Jun 18, 2016

Olive Drab Green said:
You brought up your own religion. And so did someone else, telling you that won't fly, and I concurred. I'm trying to help you, not hinder you. You had said you are still going to smoke and try to feel out the cycles. If you don't want my advice, which I'm truly giving you from my heart, I won't waste my breath, man.

I did bring up my Religion, but you brought up Marijuana and my Religion, I was talking about Soma with someone else. And that's DMT and Muscimol. They don't even test for that stuff in any drug test. You brought up that I couldn't practice the Marijuana smoking part of my Religion, and I was just explaining that I have read the drug testing rules, and you can get Marijuana anywhere in the world, and people I meet in there will be people who smoke. Like if I meet anyone from Colorado or Texas, odds are they smoke. Before Colorado Recreationally legalized the 3 highest smokers per capita in America was the area around California, Texas and the area around Florida.

Finshaggy · Jun 18, 2016

Olive Drab Green said:
I did, myself, in '09. They check your barracks room. It's called "barracks inspection. That happens every month or two. The UCMJ is the military's bylaws and while Spice is legal in the civilian world, it is illegal in the military.

If I got say a gram of something, just as an example, that could be smoked in a week, or less if like 3 or 4 people wanted to partake. And even if not, it could be passed around or gotten rid of. The stuff is like $15 a gram, and a hit is 5mg because it's pure, but you can smoke way more than 5mg. And you can put it on the end of a cigarette or something even.

Finshaggy · Jun 18, 2016

And I made the point that plants can be used to make plants that make things make other Somas, and you can make other Somas in a lab. But none of that was THC related.

Olive Drab Green · Jun 18, 2016

They will not be at all understanding. I'm serious. You have to abstain entirely, save for alcohol.

Finshaggy · Jun 18, 2016

And I know all the other plants that do things and work. Like most people looking at different plants think that when a shop or a website sells a bunch of plants that all those plants are supposed to get you high. But some of them are just meant to have an effect of your body or consciousness, not necessarily get you high. Then there are some that can get you high. But they are all meant to be used Religiously, not for fun. That is mainly where people get confused.

Just as an example that everyone knows, Salvia. It can get you high, but you are supposed to use it the way the Mazatec in Mexico use it, which is to speak to Ska Pastora (The Shepherdess).

Then there is like Kratom, which actually works, Mulungu, which actually works, Datura (which is like BZ, mentioned in the Edgewood Arsenal section of the first post).

Finshaggy · Jun 18, 2016

Olive Drab Green said:
They will not be at all understanding. I'm serious. You have to abstain entirely, save for alcohol.

If I have to I will, I already said that too. But I definitely know people who used things in the Military.

Finshaggy · Jun 18, 2016

And I really really doubt that everyone going in to CBRN is sober. Like that is really hard to believe. Anyone who is in to Chemistry is usually down to talk about Church of Neuroscience type stuff, if not actually do it.

Finshaggy · Jun 18, 2016

Strangely this thread has remained completely on topic, and I'm not sure anyone was even trying. Everything has been in the Chemical and Biological realm, but that's all on topic. Lol.

Finshaggy · Jun 18, 2016

Finshaggy · Jun 18, 2016

And you can never get in trouble doing this.

CYP450 Enzyme Discovery

Procedure

I found this page that gives dosages, for activators
http://herbpedia.wikidot.com/oilahuasca-activators

Procedure, in plain English:

Pepper would be made into a tea. Solids filtered out.

Then you would get some Anise Oil, B9 or Valerian Root (of Chinese Origin)

So that is your Pepperidine, and you activators. Now you need your Enzyme Inhibitors. You can add L-Lysine, but it is not necessary.

Vanilla and Cinnamon work, pick one or both. You also need the Aldehyde structure from one of these.

Next. German Chamomile, Cayenne Pepper Capsules or Tangerine Skin extract/capsules

Then
Almond extract, Anise Oil (if you already had it), Cinnamon, Lemon peel oil, Lime peel oil, or a cigarette or nicotine gum if you can't find anything else.

Then
CBD, Echinacea Purea, Pomegranate, Pummelo, or Calamus Oil.

Then
Clove oil, Catechin, Dill seed Oil or Goldenseal.

Then Kudzu or Glycerin or Caffeine

Not all of these things are neccisarry, but if you do 1 thing in each list, you should get very strong effects from whatever you take.

The best thing to take is Sweet Basil Extract, in it's pure form, it is known as Methyl Chavicol.

Take all that other stuff like 30 minutes to an hour before the Basil Extract, and redose the B9, Anise or Valerian root to keep the effects going without taking more.

Science

Graviola- 5-HT1a Agonist
Black Cohosh- 5-HT1A, 5-HT1D & 5-HT7 Binding
C. Foetida L.- 5-HT1A Agonist
Yokukansan- 5-HT1A Agonist
DMT hits all of these, and can be found in tons of plants.

Black Cohosh- 5-HT1D
maybe Rhodiola rosea, Albizia lebbeck & Albizia julibrissin.

5-HT1 Receptor Agonists:
Turmeric, Ginger, Ginko Bilboa, Lemon Essential Oil, Rauwolfia, Valerian, Yohimbe

Elmicin & Myristicin (in Nutmeg)- 5-HT2A Agonist
Estragole (in Sweet Basil)- 5-HT2A Agonist
Safrole (in Sassafras)- 5-HT2A Agonist

Cinnamon Bark- CYP2A6 & CYP2E1 Inhibitor (It will deplete your liver's Glutithione) Taken 1 Hour before Allybenzene,
Clove Leaf- CYP2C9, CYP3A4, CYP1A1 & CYP1B1 Inhibitor
German Chamomile- CYP1A2 Inhibitor (Caffeine may also do this)
GoldenSseal & Echinacea purpurea very effectively do the same thing.
Black seed oil, 50% EGCG, Valerian root oil, Pomegranate, Vitamin B9, 40% Ellagic extract, Rooibos 20% Gallic acid extract, Rutin, B3 & Kudzu

AllylBenzenes
Anethole, Apiol, Asarone, Carpacin, Chavibetol, Chavicol, Dillapiole, Eugenol, Isoeugenol, Isosafrole, Methyl Eugenol, Methyl Isoeugenol,

since Cinnamon is a Phenylpropanoid, and Phenylpropanoids are made from Phenelalamine, and people who took Phenelalamine claim to get better results. I decided to post a list of Phenylpropanoids also.
Caffeyl Alcohol, Cinnamaldehyde, Cinnamyl alcohol, alpha-Cyno-4-hydroxycinnamic acid, Ethyl Cinnamate, Lignin, 2,4-Methlenedioxypropiophenone, Neoflavonoids, Nordihydroguaiaretic acid, Phenylpropanoic acid, Phloretic acid, Rhododendrin & Suberin.

Star Anise Extract or B9 for CYP2C9 Induction

NMDA Receptor Plants:
Uncaria Rhynchophyllia
Psychotria Colorata
Huperzia Serrata

Most important things:
CYP2C9 Induction
Alcohol Dehydrogenase Induction
Aldehyde Dehydrogenase Inhibition
Piperidine and or Dimethylamine Supplementation
Methyl from foods
Exercise or compounds that produce effects like exercise

Less important, but still factors:
SSAO Inhibition (Caffeine, Phenethylamine, Phenelalamine, Tryptamine)
MAO-A Induction
MAO-B Induction
NDMA Antagonism
Prolactin Inhibition

Hungarian Parsley Seed is a better source of Myristicin than Nutmeg. The effects of it when activated properly are said to be like Mescaline and MDMA together. The P450 Enzymes CYP1A2 & CYP3A4 are what break this down and need to be inhibited. CYP2D6 could also play a big role.

Elmicin is something you either need Chromotography type knowledge to get, or you have to buy it in small quantities. When activated properly it is like Mescaline, when activated wrong it is like Melatonin (sleepy). CYP1A1, CYP1B1, CYP1A2, CYP2A6, CYP2C9, CYP2A6, CYP2C9 & CYP2E1 are what are needed to be inhibited to activate this. CYP2D6 could also play an important role.

Safrole is like MDMA when activated properly and like Melatonin when not. CYP2A6, CYP2C9, and CYP2E1 are most important for this. CYP2D6 could also be important.

Methyl Chavicol when activated properly is like a light speedy LSD, when activated wrong it is said to be almost like Marijuana. CYP1A2 and CYP2A6 inhibit it, and CYP2D6 could also be important.

If the CYP2D6 Enzyme is inhibited with all the others, these are possibly visually hallucinogenic Oilahuascas. And the Methyl Chavicol doesn't build a tolerance (the others do) it actually gets stronger for you every time you use it, or you can use less.

Several allylbenzenes have been proven to form up to 3 alkaloid metabolites after ingestion by several animals.[2][3] They do not form amphetamines in vivo as has been speculated in the past. The alkaloids detected in animal urine are tertiary aminopropiophenones of 3 possible subtypes: dimethylamines, piperidines, and pyrrolidines.[1][2][3][4]

The allylbenzene elemicin has been proven to form all 3 different alkaloid metabolites after ingestion in animals by analyzing urine using gas-liquid chromatography and chemical ionization mass spectrometry.[1]

Safrole is also proven to form all three alkaloid metabolites after ingestion.[2]

Myristicin appears to only form piperidines and pyrrolidines. Dimethylamines of myristicin have not been detected.[3]

Allylbenzene, from which all allylbenzenes are derived, forms piperidine and dimethylamine alkaloids.[4]

Propenylbenzene and its derivatives (asarone, anethole, etc.) do not form alkaloid metabolites.[4]

Here is how it works

CYP Enzymes (Drug Metabolism, etc)
https://www.youtube.com/watch?v=ztsBn8gsfHw

Induction and Inhibition (Anti-Oxidants, etc)
https://www.youtube.com/watch?v=7R0_TGHczRU

All inhibitors of oxidative 17bHSD2 will prevent activation of allylbenzenes. This enzyme must be induced, not inhibited. It's the single most important enzyme to induce. If oxidative 17bHSD2 is not functioning, allylbenzenes cannot produce psychedelic activity. Naringenin also potently inhibits 17bHSD2. Grapefruit contains large amounts of naringenin, and also prevents the psychedelic action of allylbenzenes if taken before allylbenzenes. Inhibition lasts approximately 4-8 hours.

Oilahuasca Diet

Here's a list of all known 17bHSD2 inhibitors that should be avoided 4-8 hours prior to using allylbenzenes:
•Quercetin and all food or supplements containing large amounts of it.
•Apples (0.0263% quercetin)[6]
•Cabbage (0.01% quercetin)[6]
•Cranberry (0.025% quercetin)[6]
•Evening-Primrose (20% quercetin)[6]
•Galangin and all food or supplements containing large amounts of it.
•Garlic (0.02% quercetin)[6]
•Grapefruit (contains naringenin, kaempferol, galangin, and quercetin)
•Himalayan Mayapple (1.2% quercetin)[6]
•Kaempferide and all food or supplements containing large amounts of it.
•kaempferol and all foods that contain large amounts it.
•Mayapple (5% quercetin)[6]
•Naringenin and all food or supplements containing large amounts of it.
•Neem (0.1% Quercetin)[6]
•Oats (0.031% Quercetin)[6]
•Onions (4.81% quercetin).[6]
•Orange (4.58% naringenin)[6]
•Tea (10-25 mg/L quercetin, 6.3-17 mg/L kaempferol [7]).[6]
•Tomato (contains kaempferol, naringenin)
•Yuzu (contains naringenin)

Finshaggy · Jun 18, 2016

The benzene ring has 6 positions. In the graphical layout given below the following color guide is used:

position 1 = black (the important allyl side chain, required for conversion to an alkaloid)
position 2 = brown (a methoxy group here seems to cause LSD-like mental effects)
position 3 = red
position 4 = green (must be a methoxy or methylenedioxy group for psychedelic activity)
position 5 = blue (a methoxy or methylenedioxy group here seems to enhance visuals)
position 6 = purple (a methoxy group here probably adds speedy effects)

Position 1 has the allyl side chain hanging off of it. It's the same for all allylbenzenes. This is the part of the allylbenzene that reacts in the body to form a dimethylamine, piperidine, or pyrrolidine alkaloid, if digested properly. The details of this are discussed elsewhere.

In order to have psychedelic activity, position 4 must be a methoxy group. It can be tied to another methoxy group on position 5, as it is with myristicin and others. Two methoxy groups tied together are called a methylenedioxy group.

Position 4 cannot be a hydroxy group as it is in eugenol, hydroxychavicol, and chavicol. This can only lead to stimulant effects, not psychedelic effects.

At the bottom of the chart you can see eugenol, hydroxychavicol, and chavicol. These posses no psychedelic activity, even when properly metabolized. These are the only allylbenzenes in the chart that have a hydroxy group on the 4 position.

Above that we have methyl eugenol, chavibitol, and methyl chavicol. Methyl chavicol and methyl eugenol have psychedelic activity when properly metabolized. The effects of chavibitol are unknown, but are probably like a cross between methyl eugenol and methyl chavicol. The 5 position being a methoxy group seems to improve visual effects.

Above that we have croweacin, apiole, and safrole. Apiole and safrole are psychedelic when metabolized properly. Croweacin is a positional isomer of myristicin. It's activity is not known. It's very likely similar to myristicin, but probably more speedy like apiole. The 6 position being a methoxy group seems to add amphetamine style speedy effects.

Above that we have the ever so popular myristicin, and then dillapiole and the rare sarisan. Both myristicin and dillapiole are psychotic when properly metabolized. The activity of sarisan is unknown. It is a positional isomer of myristicin. It has a methoxy group on the 2 position instead of the 3 position. This probably gives it LSD-like mental effects which are attributed to dillapiole and gamma-asarone rather than myristicin.

Above that we have elemicin, 2,3,4,5-tetramethoxy-allylbenzene, and gamma-asarone. Elemicin is the only one of these that's known to have psychedelic activity when properly metabolized. When properly metabolized, it's effects are similar to myristicin, but more like mescaline. It has the same positional substitutions as myristicin, only the 4 and 5 positions are not tied together. Gamma-asarone is a positional isomer of elemicin and is probably the main active psychedelic compound in calamus oil from Nepal. The methoxy group on the 2 position is probably the reason calamus oil from Nepal has LSD-like mental effects shared by dillapiole and absent from most of the other allylbenzenes. I have no idea if 2,3,4,5-tetramethoxy-allylbenzene is active or not.

(CBRN) Chemical, Biological, Radiological & Nuclear

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