Fucking GROSS!! - I do appreciate the info guys!
Myclobutanil
Chemical Description
Myclobutanil is a white crystal solid. It is mobile in soil, and has a solubility in water of 142 mg/L (
#EPA).
Myclobutanil is commercially available as granular dust, dry flowable, and ready-to-use formulations (
#EPA).
Uses
Myclobutanil is registered for use on a wide range of food and feed crops. It may also be used in greenhouses, public rights of way, turf, and in landscaping applications. Cotton seeds may be treated with myclobutanil (
#EPA).
California accounts for roughly 50% of all myclobutanil use in the US, using 70,000 to 90,000 lbs. annually. Grapes are the most heavily treated crop, using 60% of all myclobutanil in California. Almonds and strawberries are also account for a notable percentage of myclobutanil use in California (
#EPA).
Human Health Effects
Myclobutanil has a relatively low acute toxicity. The acute oral LD50 for mice is 1360 mg/kg, and ranges from 1.75 to 1.8 g/kg for rats. Myclobutanil metabolizes into 1,2,4-triazole, which has a lower acute toxicity than the parent compound (
#EPA).
Workers exposed to myclobutanil have reported symptoms such as skin rash, allergic dermatitis, itchiness, nausea, heachache, diarrhea, abdominal pain, vomiting, nosebleed, and eye irritation (CDPR).
In a two-generation study on rats over the effects of myclobutanil on reproduction, researchers found a decrease in pup weight gain, increased incidence of stillborns, and atrophy of the testes and prostate (
#EPA). Myclobutanil is listed as a developmental toxin in the
Toxics Release Inventory (
#PANNA).
Chronic toxicity tests on rats found decreased body weight and changes to brain and spleen weight, in addition to reproductive effects (
#EPA).
Environmental Health Effects
Myclobutanil inhibits the sterol 14-demethylase enzyme, which produces ergosterol, an organic compound vital to fungal cell wall formation (
#EPA).
Myclobutanil is nontoxic to bees, which have an LD50 exceeding 362 ug/bee. It is moderately toxic to birds. The acute oral LD50 for bobwhite quail is 498 mg/kg. The primary metabolite, 1,2,4-triazole, is expected to be less toxic than myclobutanil (
#EPA).
Myclobutanil is environmentally mobile. It has been found in surface water and in rain, suggesting a potential for atmospheric transport. Due to its persistence, myclobutanil may accumulate in soil with multiple applications (
#EPA).
Regulation
Myclobutanil is a General Use Pesticide.
Precautionary Notes
Myclobutanil can become airborne as a dust. In high concentrations, it can become an explosive mixture in the air. Burning myclobutanil may release toxic fumes.
LP Bastards!!
I'm not eating non-organic grapes or strawberries anymore either!