This is something I have been working on for some time now, and my process is continually changing/evolving, but the basic idea is just some extract, be it bho/qwiso/qwet etc cut with coconut oil. My process right now is extracting the oil from completely dried and slightly ground cannabis via a QWISO method that I will describe below.
I use 99% ISO that has been in the freezer overnight, along with the dried flower that has been frozen as well. I do 2-3 15 second washes of the flower and quickly strain it through a 180 micron filter to remove the bulk of the plant material.The liquid is then filtered again through a 25 micron filter, and then again through a 10 micron lab filter under vacuum. The 10 micron filtering is not really necessary for capsules, but I refine my oil to be used in both caps and vaporizers, and the extra filtering helps make a cleaner product for the ladder.
After I have done my filtering I usually throw my jars of refined liquid in the freezer again for 24 hours or so to let any remaining solids settle or solidify, which I will then filter out again with the 10 micron lab filter. You could also decant the liquid and leave behind the solids if you so desired.
From here I evaporate the alcohol away in a Pyrex baking dish, placed on a temp controlled electric griddle set to a fairly low temp. Most people will advise that you evap naturally at room temp with a fan, but I simply don't have the time to slowly evaporate such a large quantity of alcohol (1-2 gallons), nor do I want to be running an extraction fan for several days during that process. So because of this, I evap on the griddle at around 150f, which combined with an extraction fan, only takes a few hours. After the alcohol is gone I let the oil sit at room temp for a few days.
The product that I am left with is very sticky and hard, much like a harder pine tar. I find it is usually easiest to heat the oil back up enough to thin it enough to suck up in a syringe, which I then transfer to a beaker for decarbing on a hot plate. I decarb the oil for around 25-30 min at 250 on a digital hotplate with a magnetic stirrer to prevent overheating. Once the oil is decarbed I transfer back to syringes and store in the fridge for use.
To make my caps I cut the oil 1:1 cannabis oil to coconut oil (melted beforehand), usually 10 grams of each at a time, and mix in a small amount of sunflower lecithin. I heat this mix up and stir it on the hotplate for 10-15 min at around 130f, and then suck it up into syringes. Right now I am using size 1 capsules since that is the largest the my mother can easily swallow. It is easiest to fill these with a filter or blunt tip needle. I dose these to her four times a day, and slowly titrated the dose up from 1:10 to 1:1. Each one of the caps she takes contains about 185mg (lab tested), for roughly 750mg a day.
You can play with the doses and amounts, but I have found that high doses are important in treating the worst of conditions like cancer, parkinsons etc. Consistency in caps and continuity of care is also very important. Bear in mind that making doses this large can be difficult, and will require a significant amount of dried flower, but it is pretty easy to get started with small 1:20 or 1:10 doses. Each extraction that I do will yield around 50-60 grams of oil in the pyrex dish after evap, and that will last around 3 months. I'm sure I'm forgetting some other stuff, but the only other thing I have to add right now is to avoid "green" extracts like RSO, as I have found that the excessive chlorophyll causes moderate nausea which I don't want, especially in a patient who already suffers bad nausea to begin with.
