I think there is selfish gene that will prevent seeds to be viable. But I think none of the cannabis seed companies use it. They use this method it in corn grow in USA to prevent competition and watermelon in Israel cause ppl don’t like to spit seeds (bit surprising as we do like to spit each other).
As far as I know u can cross any cannabis strain u want and seeds will sprout.
I grow photo period for many years and I always start from seeds. I do seeds run from time to time (once evert 2 years or so).
This winter I decided to try autoflower for the first time. I grow in the etic and temp is very low, 10-15C in the winter. (in have narrow space as well)
I got my seeds from Amsterdam seed center. They give freebies, store all seeds in fridge and have tons of variety including regular auto (regular are rare in Europe)
i got These this winter:
Auto Sweet skunk F – I saw many good reviews on it and for a good reason. It might be the best strain I had so far, auto or not. It takes 65 days and has great taste and smoke. Only bad thing is medium yield, but I think it will be hard to match auto yield to photoperiod. It was so good that ill probably stick to sweet seeds only in my next purchase. (Only company I saw that print package date and give freebie inside the package)
Auto lemon haze regular by emerald – all sprout but only 50% are auto. Got one nice male that almost finished in 30 days. Females were ok, Decent smoke but no lemon at all
Auto Tao mix regular – none sprout, but I blame myself for choosing niche seed package.
I have lemon haze cross with lemon haze and sweet skunk seeds. I hope to gain bit more experience with auto as yield is almost half compare to photoperiod (it was cold winter in Europe this year, let’s hope summer will be better)