I start my seeds in Rapid Rooters and place them in a 3-1/2 gallon buckets filled with a 5:1 perlite/vermiculite ratio. I drill 2 holes in the bucket - one at the 2" from the bottom and one at the bottom. I start feeding every few hours by watering around the sprout to keep it moist. The reason for the bottom hole is because the roots aren't drinking from the bottom 2" yet and I don't want the res to stagnate - once the roots reach the bottom I tape up the bottom hole.
I highly suggest you rinse your perlite thoroughly because there is a lot of dust and when wet turns into white dense mud - not good for the roots. I fill 2- 5 gal. buckets with water and pour some perlite in the first bucket, swish it around, scoop out what floats, place in the second bucket, swish it around, and scoop out into my hempy buckets. You'll be amazed at how much gunk powder sinks to the bottom of the first bucket.
I grew in coco for years with great success, but I find hempys easier - very fast growth, no salt build up, you only feed every other day instead of multiple feedings a day in coco, and no fungus gnats.
Good luck with your grow.
Edit PS - consider covering your perlite mix with pebbles or something to avoid algae growth - I use small river pebbles.