Pandemic 2020
- Thread starter Jimdamick
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task force is back by popular demand.
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DIY-HP-LED
Well-Known Member
Here's something interesting that could cut covid-19 mortality rates significantly, if deployed properly, more study is required, but blood thinners are used for this purpose anyway and it's not even an off label use. An over doubling of the survival rate for those on ventilators is significant IMHO!
This might whittle the mortality rate down quite a bit on it's own, in developed countries at least.
"A total of 395 were placed on ventilators. Among those who weren't given a type of blood thinner called an anticoagulant, 62.7 percent died, compared with 29.1 percent of those who were given the medications."
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www.nbcnews.com
CORONAVIRUS
For sickest patients, blood thinners may be linked to reduced COVID-19 deaths, study finds
Faced with an increased risk of blood clots, patients with the coronavirus may benefit from blood thinning medications.
Blood thinners may help keep COVID-19 patients on ventilators alive longer, a study published Wednesday suggests.
In recent weeks, physicians have noticed that the sickest coronavirus patients are more prone to forming blood clots — an unexpected symptom for a respiratory virus.
Full coverage of the coronavirus outbreak
Clotting means "patients are at increased risk for deep vein thrombosis, strokes, heart attacks" and pulmonary embolisms, said Dr. Hugh Cassiere, a pulmonologist and the medical director of Respiratory Care Services at North Shore University Hospital on Long Island, New York.
Now, early data indicates that using these drugs may be beneficial.
In a study published Wednesday in the Journal of the American College of Cardiology, researchers at Mount Sinai Health System analyzed the health records of 2,773 COVID-19 patients.
A total of 395 were placed on ventilators. Among those who weren't given a type of blood thinner called an anticoagulant, 62.7 percent died, compared with 29.1 percent of those who were given the medications.
"Using anticoagulants should be considered when patients get admitted to the ER and have tested positive for COVID-19 to possibly improve outcomes," Dr. Valentin Fuster, the study's author and director of Mount Sinai Heart, wrote in a press release. However, Fuster added doctors should also carefully consider whether patients may have an increased risk for bleeding.
"This is an observational study and should be interpreted with caution," Fuster told NBC News. That means the research cannot prove the anticoagulants indeed led to fewer deaths or had any real therapeutic impact. More research, including randomized trials, will be needed to answer those questions.
Cassiere agreed. "This study doesn't help us figure that out, but it is helpful because we've been anticoagulating these patients anyway based on no data."
Anecdotally, the drugs are working.
more...
This might whittle the mortality rate down quite a bit on it's own, in developed countries at least.
"A total of 395 were placed on ventilators. Among those who weren't given a type of blood thinner called an anticoagulant, 62.7 percent died, compared with 29.1 percent of those who were given the medications."
---------------------------------------------------------------------------------------------------------------------------------------------------
For sickest patients, blood thinners may be linked to reduced COVID-19 deaths, study finds
Faced with an increased risk of blood clots, patients with the coronavirus may benefit from blood thinning medications.
CORONAVIRUS
For sickest patients, blood thinners may be linked to reduced COVID-19 deaths, study finds
Faced with an increased risk of blood clots, patients with the coronavirus may benefit from blood thinning medications.
Blood thinners may help keep COVID-19 patients on ventilators alive longer, a study published Wednesday suggests.
In recent weeks, physicians have noticed that the sickest coronavirus patients are more prone to forming blood clots — an unexpected symptom for a respiratory virus.
Full coverage of the coronavirus outbreak
Clotting means "patients are at increased risk for deep vein thrombosis, strokes, heart attacks" and pulmonary embolisms, said Dr. Hugh Cassiere, a pulmonologist and the medical director of Respiratory Care Services at North Shore University Hospital on Long Island, New York.
Now, early data indicates that using these drugs may be beneficial.
In a study published Wednesday in the Journal of the American College of Cardiology, researchers at Mount Sinai Health System analyzed the health records of 2,773 COVID-19 patients.
A total of 395 were placed on ventilators. Among those who weren't given a type of blood thinner called an anticoagulant, 62.7 percent died, compared with 29.1 percent of those who were given the medications.
"Using anticoagulants should be considered when patients get admitted to the ER and have tested positive for COVID-19 to possibly improve outcomes," Dr. Valentin Fuster, the study's author and director of Mount Sinai Heart, wrote in a press release. However, Fuster added doctors should also carefully consider whether patients may have an increased risk for bleeding.
"This is an observational study and should be interpreted with caution," Fuster told NBC News. That means the research cannot prove the anticoagulants indeed led to fewer deaths or had any real therapeutic impact. More research, including randomized trials, will be needed to answer those questions.
Cassiere agreed. "This study doesn't help us figure that out, but it is helpful because we've been anticoagulating these patients anyway based on no data."
Anecdotally, the drugs are working.
more...
Last edited:
DIY-HP-LED
Well-Known Member
For the sake of discussion, let's say without effective treatments and the current government federal policy (chaos) 1 million Americans would die, until a vaccine is developed. The most reliable mortality rate data I could find is .5% with good care in a developed country, that's one in every 200 people who die.
Say for the sake of argument that 100 of those people end up on a ventilator and the anticoagulant therapy mentioned above, over twice as many live now as before. In addition others who are not on ventilators are saved as well, especially younger patients, and never get to to a ventilator.
The mortality rate might go from .5% to .4% or even .3% if it is refined with better anticoagulant medications and treatment protocols, by using this treatment option alone. This might be one of many treatment options coming online now, along with redesivir and convalescent plasma therapy, provided studies confirm what is strongly suggested by the preliminary data. These three therapies could take a serious bite out of the mortality rate by summer and drive it below .09% or lower. Other antibody therapies are expected to be deployed by the end of summer and they might drive the mortality rate even lower. There are also other antiviral drugs that might be deployed this summer that attack different SARSCov 2 enzymes than remdesivir and might provide even more treatment options.
.1% of Americans dying will require a lot less body bags than if .5% die and if we can drive it down to .05%, is an order of magnitude better than no effective treatment options, its many orders of magnitude of less suffering. We need a bridge to a vaccine or ethical herd immunity, we might soon have several.
Say for the sake of argument that 100 of those people end up on a ventilator and the anticoagulant therapy mentioned above, over twice as many live now as before. In addition others who are not on ventilators are saved as well, especially younger patients, and never get to to a ventilator.
The mortality rate might go from .5% to .4% or even .3% if it is refined with better anticoagulant medications and treatment protocols, by using this treatment option alone. This might be one of many treatment options coming online now, along with redesivir and convalescent plasma therapy, provided studies confirm what is strongly suggested by the preliminary data. These three therapies could take a serious bite out of the mortality rate by summer and drive it below .09% or lower. Other antibody therapies are expected to be deployed by the end of summer and they might drive the mortality rate even lower. There are also other antiviral drugs that might be deployed this summer that attack different SARSCov 2 enzymes than remdesivir and might provide even more treatment options.
.1% of Americans dying will require a lot less body bags than if .5% die and if we can drive it down to .05%, is an order of magnitude better than no effective treatment options, its many orders of magnitude of less suffering. We need a bridge to a vaccine or ethical herd immunity, we might soon have several.
Justin-case
Well-Known Member
Ordered a new tile saw today, spoke with a gentleman from Knoxville. He said the lines were out the doors at Mexican food restaurants yesterday. I was speechless. Wtf? Round two, coming up.
DIY-HP-LED
Well-Known Member
Where are ya? TN
i think it's great that Tubbies money is going for payroll and they have some left over for improvements
DIY-HP-LED
Well-Known Member
The red states who are opening with large populations who are buying into Trump's bullshit are gonna be decimated, he's gonna do a Jim Jones on his own base. The slaughter in the red states, he should have them good ole boys primed for november, MAGA! I'll bet a few red state governors and senators will be sweating soon
topcat
Well-Known Member
The U.S. is #41 in the world in testing per 1 million people, but by all means, spin it.OMG24:00
Edit: I made it to 28:00, can anyone top that?
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DIY-HP-LED
Well-Known Member
Chris Hayes: The White House Has A Plan. It Just Doesn’t Involve You Or Me. | All In | MSNBC
The White House has implemented a robust testing regime to bring normalcy to the daily lives of the President and Vice President. So, they actually do have a plan. They are just applying it for two people. Aired on 05/06/2020.
The White House has implemented a robust testing regime to bring normalcy to the daily lives of the President and Vice President. So, they actually do have a plan. They are just applying it for two people. Aired on 05/06/2020.
Budzbuddha
Well-Known Member
New puppet for the stupid puppet show ....OMG
Justin-case
Well-Known Member
North eastern California in the Sierra Nevada mountains.
DIY-HP-LED
Well-Known Member
I thought so, ya threw me when ya said knoxville.
hanimmal
Well-Known Member
The power of being able to micro-target your cult.
DIY-HP-LED
Well-Known Member
These are the '10 plain truths' about the coronavirus pandemic, according to former CDC Director Dr. Tom Frieden
Dr. Tom Frieden, the former director of the US Centers for Disease Control and Prevention, laid out "10 plain truths" about Covid-19 on Wednesday as he spoke at a House Appropriations Committee hearing on the pandemic response.
www.cnn.com
These are the '10 plain truths' about the coronavirus pandemic, according to former CDC Director Dr. Tom Frieden
(CNN)Dr. Tom Frieden, the former director of the US Centers for Disease Control and Prevention, laid out "10 plain truths" about Covid-19 on Wednesday as he spoke at a House Appropriations Committee hearing on the pandemic response.
"In my 30 years in global public health, I've never seen anything like this," Frieden, who now serves as president and CEO of Resolve to Save Lives, said. "It's scary. It's unprecedented."
Here are the 10 truths, according to Frieden:
1. "It's really bad" in New York City
"Even now with deaths decreasing substantially, there are twice as many deaths from Covid-19 in New York City as there are on a usual day from all other causes combined," Frieden said.
New York has the most confirmed coronavirus cases of any state in the country, with 321,192 total cases and 25,231 deaths, according to Johns Hopkins University data. In New York City alone, there are 173,288 cases with 43,676 hospitalized and 13,938 confirmed deaths.
2. It's "just the beginning"
Frieden said as bad as things seem now, he thinks we're still in the beginning phases of the pandemic.
Experts John Barry and Marc Lipsitch co-authored a new report that predicts that the coronavirus pandemic could last up to two more years, and they warn that the situation could get "considerably worse than what we've seen so far."
3. Data is a "very powerful weapon against this virus"
Frieden explained that data being used to monitor trends can help stop clusters before they turn into outbreaks. Data, he said, can help stop outbreaks from turning into epidemics.
Stanford University epidemiologist Dr. John Ioannidis has found from emerging data that coronavirus infections are more common than experts initially thought, and the risk of dying for the average person is lower than was first projected.
4. We need to "box the virus in"
While stay-at-home orders slowed the spread of the virus and flattened the curve in states such as New York and California, the virus continues to spread throughout the country with approximately 30,000 new cases a day for nearly a month.
With states across the US considering easing restrictions, the country opens itself up to infections increasing. That's why, Frieden said, we need to box in the coronavirus once the curve begins to flatten.
5. We must find the balance
The economy doesn't have to come at the expense of public health. Dr. Frieden said it is necessary to find the balance between restarting our economy and letting the virus run rampant.
A model from the Institute for Health Metrics and Evaluation at the University of Washington has released a revised toll that suggests that 134,000 Americans could die by August, likely taking into account the impact of state openings. And a draft internal report by the US Centers for Disease Control and Prevention that was obtained by The New York Times found that the daily death toll could reach 3,000 by June 1.
6. Protect the "frontline heroes"
"We must protect the health care workers and other essential staff, or the frontline heroes of this war," Frieden said.
According to an estimate by the CDC, more than 9,200 health care workers have been infected by the coronavirus.
Health care workers and essential staff are at the most risk, and hospitals have faced shortages of essential protective gear such as N95 masks to protect them.
7. Protect our most vulnerable people, too
Eight out of 10 deaths reported in the US have been from adults that are 65 years old and older, according to the CDC. And people with weak immune systems and underlying conditions such as asthma, heart disease, high blood pressure or diabetes are at more risk.
"In your everyday life, you're always fighting off pathogens," CNN Chief Medical Correspondent Dr. Sanjay Gupta said. "Most of the time you don't even realize it. If you have an underlying condition, it makes it more challenging to fight off a virus like this. You may develop a fever, shortness of breath or a cough more easily than someone who doesn't have a preexisting illness."
8. Governments and private companies need to work together
Both government and industry must collaborate to make "massive continued investments in testing and distributing a vaccine as soon as possible," Frieden said.
Dr. Anthony Fauci, the head of the National Institute of Allergy and Infectious Diseases, said in March that a vaccine could potentially be available in a year to 18 months. However, experts are skeptical.
"I don't think it's ever been done at an industrial scale in 18 months," said Dr. Amesh Adalja, a senior scholar focused on emerging infectious disease at the Center for Health Security at Johns Hopkins University. "Vaccine development is usually measured in years, not months."
A coronavirus vaccine trial on humans has already begun in the UK.
9. We must not neglect non-Covid health issues
While the coronavirus pandemic has flooded and overwhelmed many hospitals with patients across the world, people are no longer suddenly immune to other diseases and sicknesses. Many elective procedures have been canceled or postponed, and patients with other illnesses wait in fear as they put treatment on hold. Many are too scared to venture out and visit hospitals out of fear of contracting the virus.
10. Preparedness is paramount
"Never again," Frieden said. "It is inevitable that there will be future outbreaks. It's not inevitable that we will continue to be so underprepared."
Jimdamick
Well-Known Member
I never would have thought he could be for eloquent.
“As far as I’m concerned anyone can enjoy GNR 4 whatever reason n’ there’s truth 2 the saying ‘u can’t choose your fans’ n’ we’re good w/that… Having said that my personal position is that the Trump administration along w/the majority of Republicans in Congress n’ their donors that support him 4 their own agendas r doing r nation a disservice… We have an individual in the WH that will say n’ do anything w/no regard for truth, ethics, morals or empathy of any kind, who says what’s real is fake n’ what’s fake is real… Who will stop at nothing 4 power feeding off the anger n’ resentment he sows 24/7 while constantly whining how whatever doesn’t go his way is unfair… Most of us in America have never experienced anything this obscene at this level in r lifetimes n’ if we as a country don’t wake up n’ put an end 2 this nonsense now it’s something we definitely will all pay hard 4 as time goes on.”
Guess who wrote that?
I'll give you a hint
“As far as I’m concerned anyone can enjoy GNR 4 whatever reason n’ there’s truth 2 the saying ‘u can’t choose your fans’ n’ we’re good w/that… Having said that my personal position is that the Trump administration along w/the majority of Republicans in Congress n’ their donors that support him 4 their own agendas r doing r nation a disservice… We have an individual in the WH that will say n’ do anything w/no regard for truth, ethics, morals or empathy of any kind, who says what’s real is fake n’ what’s fake is real… Who will stop at nothing 4 power feeding off the anger n’ resentment he sows 24/7 while constantly whining how whatever doesn’t go his way is unfair… Most of us in America have never experienced anything this obscene at this level in r lifetimes n’ if we as a country don’t wake up n’ put an end 2 this nonsense now it’s something we definitely will all pay hard 4 as time goes on.”
Guess who wrote that?
I'll give you a hint
Jimdamick
Well-Known Member
And then that fucking "it" does thisThese are the '10 plain truths' about the coronavirus pandemic, according to former CDC Director Dr. Tom Frieden
Dr. Tom Frieden, the former director of the US Centers for Disease Control and Prevention, laid out "10 plain truths" about Covid-19 on Wednesday as he spoke at a House Appropriations Committee hearing on the pandemic response.
These are the '10 plain truths' about the coronavirus pandemic, according to former CDC Director Dr. Tom Frieden
(CNN)Dr. Tom Frieden, the former director of the US Centers for Disease Control and Prevention, laid out "10 plain truths" about Covid-19 on Wednesday as he spoke at a House Appropriations Committee hearing on the pandemic response.
"In my 30 years in global public health, I've never seen anything like this," Frieden, who now serves as president and CEO of Resolve to Save Lives, said. "It's scary. It's unprecedented."
Here are the 10 truths, according to Frieden:
1. "It's really bad" in New York City
"Even now with deaths decreasing substantially, there are twice as many deaths from Covid-19 in New York City as there are on a usual day from all other causes combined," Frieden said.
New York has the most confirmed coronavirus cases of any state in the country, with 321,192 total cases and 25,231 deaths, according to Johns Hopkins University data. In New York City alone, there are 173,288 cases with 43,676 hospitalized and 13,938 confirmed deaths.
2. It's "just the beginning"
Frieden said as bad as things seem now, he thinks we're still in the beginning phases of the pandemic.
Experts John Barry and Marc Lipsitch co-authored a new report that predicts that the coronavirus pandemic could last up to two more years, and they warn that the situation could get "considerably worse than what we've seen so far."
3. Data is a "very powerful weapon against this virus"
Frieden explained that data being used to monitor trends can help stop clusters before they turn into outbreaks. Data, he said, can help stop outbreaks from turning into epidemics.
Stanford University epidemiologist Dr. John Ioannidis has found from emerging data that coronavirus infections are more common than experts initially thought, and the risk of dying for the average person is lower than was first projected.
4. We need to "box the virus in"
While stay-at-home orders slowed the spread of the virus and flattened the curve in states such as New York and California, the virus continues to spread throughout the country with approximately 30,000 new cases a day for nearly a month.
With states across the US considering easing restrictions, the country opens itself up to infections increasing. That's why, Frieden said, we need to box in the coronavirus once the curve begins to flatten.
5. We must find the balance
The economy doesn't have to come at the expense of public health. Dr. Frieden said it is necessary to find the balance between restarting our economy and letting the virus run rampant.
A model from the Institute for Health Metrics and Evaluation at the University of Washington has released a revised toll that suggests that 134,000 Americans could die by August, likely taking into account the impact of state openings. And a draft internal report by the US Centers for Disease Control and Prevention that was obtained by The New York Times found that the daily death toll could reach 3,000 by June 1.
6. Protect the "frontline heroes"
"We must protect the health care workers and other essential staff, or the frontline heroes of this war," Frieden said.
According to an estimate by the CDC, more than 9,200 health care workers have been infected by the coronavirus.
Health care workers and essential staff are at the most risk, and hospitals have faced shortages of essential protective gear such as N95 masks to protect them.
7. Protect our most vulnerable people, too
Eight out of 10 deaths reported in the US have been from adults that are 65 years old and older, according to the CDC. And people with weak immune systems and underlying conditions such as asthma, heart disease, high blood pressure or diabetes are at more risk.
"In your everyday life, you're always fighting off pathogens," CNN Chief Medical Correspondent Dr. Sanjay Gupta said. "Most of the time you don't even realize it. If you have an underlying condition, it makes it more challenging to fight off a virus like this. You may develop a fever, shortness of breath or a cough more easily than someone who doesn't have a preexisting illness."
8. Governments and private companies need to work together
Both government and industry must collaborate to make "massive continued investments in testing and distributing a vaccine as soon as possible," Frieden said.
Dr. Anthony Fauci, the head of the National Institute of Allergy and Infectious Diseases, said in March that a vaccine could potentially be available in a year to 18 months. However, experts are skeptical.
"I don't think it's ever been done at an industrial scale in 18 months," said Dr. Amesh Adalja, a senior scholar focused on emerging infectious disease at the Center for Health Security at Johns Hopkins University. "Vaccine development is usually measured in years, not months."
A coronavirus vaccine trial on humans has already begun in the UK.
9. We must not neglect non-Covid health issues
While the coronavirus pandemic has flooded and overwhelmed many hospitals with patients across the world, people are no longer suddenly immune to other diseases and sicknesses. Many elective procedures have been canceled or postponed, and patients with other illnesses wait in fear as they put treatment on hold. Many are too scared to venture out and visit hospitals out of fear of contracting the virus.
10. Preparedness is paramount
"Never again," Frieden said. "It is inevitable that there will be future outbreaks. It's not inevitable that we will continue to be so underprepared."
DIY-HP-LED
Well-Known Member
At least 35% to 40% of the people will vote for him no matter what and they are gonna live and some die through the what. His scheme to force the economy back up again will backfire right into his face, all the red states and those who believe him are gonna get fucked over by the plague next, they are the ones opening up and lot's more republicans believe "don't need no stinkin mask"! I tell ya James Trump's koolaid is gonna kill some of the dumb bastards and kick the living shit out of a lot more of em. I wonder if he's gonna be holding any red state rallies, if he does he'll leave a trail of death and overwhelmed hospitals behind him, his fans won't social distance when sick and will infect lots more folks.
You'll see them start to die off in a month and if they stay stupid it's gonna get very bad for them for a long time, by november they will be fucked. The blue states that follow the advice of experts and where people wear masks shouldn't be affected as much, the red states will be hammered this summer though.
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