Pandemic 2020
- Thread starter Jimdamick
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printer
Well-Known Member
The nasty one?
Dr.Amber Trichome
Well-Known Member
Wow J and J really screwed up. a couple workers at the Baltimore plant ruined 15 million doses! I was wondering what was going on with the roll out. What an unfortunate mistake.
captainmorgan
Well-Known Member
Ontario is going into lockdown for a month.
printer
Well-Known Member
You are not suppose to pee in the vat unless it is beer you are making.
doublejj
Well-Known Member
Sarah Palin is now part of the Deep State......
people.com
Sarah Palin Reveals COVID Diagnosis and 'Bizarre' Symptoms, Urges Others to Continue Wearing Masks
Sarah Palin has tested positive for COVID-19, and she's urging others to continue taking the pandemic seriously
captainmorgan
Well-Known Member
It's a nice change having someone that gives a shit running the country.
www.fda.gov
Coronavirus (COVID-19) Update: FDA Continues to Advance Over-the Counter and Other Screening Test Development
FDA Continues to Advance COVID-19 Test Development.
DIY-HP-LED
Well-Known Member
Human immune systems have been in the war for a very long time and perhaps have evolved ways of dealing with viral variants, since most viruses mutate.
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Your Immune System Evolves to Fight Coronavirus Variants - Scientific American
Your Immune System Evolves to Fight Coronavirus Variants
Antibodies can change to counter new forms of the shape-shifting virus, research hints
A lot of worry has been triggered by discoveries that variants of the pandemic-causing coronavirus can be more infectious than the original. But now scientists are starting to find some signs of hope on the human side of this microbe-host interaction. By studying the blood of COVID survivors and people who have been vaccinated, immunologists are learning that some of our immune system cells—which remember past infections and react to them—might have their own abilities to change, countering mutations in the virus. What this means, scientists think, is that the immune system might have evolved its own way of dealing with variants.
“Essentially, the immune system is trying to get ahead of the virus,” says Michel Nussenzweig, an immunologist at the Rockefeller University, who conducted some recent studies that tracked this phenomenon. The emerging idea is that the body maintains reserve armies of antibody-producing cells in addition to the original cells that responded to the initial invasion by SARS-CoV-2, the virus that causes COVID. Over time some reserve cells mutate and produce antibodies that are better able to recognize new viral versions. “It’s really elegant mechanism that that we’ve evolved, basically, to be able to handle things like variants,” says Marion Pepper, an immunologist at the University of Washington, who was not involved in Nussenzweig’s research. Whether there are enough of these cells, and their antibodies, to confer protection against a shape-shifting SARS-CoV-2 is still being figured out.
Last April, when the pandemic was reaching its first peak in New York City, Nussenzweig and his colleagues sprang into action and began collecting the blood of COVID survivors. There were disturbing early reports of reinfection and waning antibodies, and the scientists wanted to understand how long the immune system could sustain its ability to respond to the novel threat. They took blood samples from people who had been hit by SARS-CoV-2 one month after the infection and then again six months later. What the scientists found was somewhat encouraging. Blood collected at the later date did have lower levels of circulating antibodies, but that made sense because the infection had cleared. And levels of the cells that make antibodies, called memory B cells, remained constant or even increased in some people over time. After an infection, these cells hang around in the body’s lymph nodes and maintain the ability to recognize the virus. If a person gets infected a second time, memory B cells activate, quickly produce antibodies and block the virus from creating a second serious infection.
In a follow-up test, the Rockefeller scientists cloned these reserve B cells and tested their antibodies against a version of SARS-CoV-2 designed to look like one of the new variants. (The experimental virus lacked the ability to replicate, which made it safer to use in the lab.) This virus had been genetically engineered to have specific mutations in its spike protein, the part of the coronavirus that attaches to human cells. The mutations mimicked a few of the ones currently found in the variants of concern. When researchers tested the reserve cells against this mutated virus, they saw some cells produced antibodies that glommed on to the mutated spike proteins—even though these spikes were different than those on the original virus. What this means is that the antibodies had changed over time to recognize different viral features. The research was published in Nature in January. “What the paper shows us is that, in fact, the immune response is evolving—that there’s some dynamic changes over this period of time,” Nussenzweig says.
more...
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Your Immune System Evolves to Fight Coronavirus Variants - Scientific American
Your Immune System Evolves to Fight Coronavirus Variants
Antibodies can change to counter new forms of the shape-shifting virus, research hints
A lot of worry has been triggered by discoveries that variants of the pandemic-causing coronavirus can be more infectious than the original. But now scientists are starting to find some signs of hope on the human side of this microbe-host interaction. By studying the blood of COVID survivors and people who have been vaccinated, immunologists are learning that some of our immune system cells—which remember past infections and react to them—might have their own abilities to change, countering mutations in the virus. What this means, scientists think, is that the immune system might have evolved its own way of dealing with variants.
“Essentially, the immune system is trying to get ahead of the virus,” says Michel Nussenzweig, an immunologist at the Rockefeller University, who conducted some recent studies that tracked this phenomenon. The emerging idea is that the body maintains reserve armies of antibody-producing cells in addition to the original cells that responded to the initial invasion by SARS-CoV-2, the virus that causes COVID. Over time some reserve cells mutate and produce antibodies that are better able to recognize new viral versions. “It’s really elegant mechanism that that we’ve evolved, basically, to be able to handle things like variants,” says Marion Pepper, an immunologist at the University of Washington, who was not involved in Nussenzweig’s research. Whether there are enough of these cells, and their antibodies, to confer protection against a shape-shifting SARS-CoV-2 is still being figured out.
Last April, when the pandemic was reaching its first peak in New York City, Nussenzweig and his colleagues sprang into action and began collecting the blood of COVID survivors. There were disturbing early reports of reinfection and waning antibodies, and the scientists wanted to understand how long the immune system could sustain its ability to respond to the novel threat. They took blood samples from people who had been hit by SARS-CoV-2 one month after the infection and then again six months later. What the scientists found was somewhat encouraging. Blood collected at the later date did have lower levels of circulating antibodies, but that made sense because the infection had cleared. And levels of the cells that make antibodies, called memory B cells, remained constant or even increased in some people over time. After an infection, these cells hang around in the body’s lymph nodes and maintain the ability to recognize the virus. If a person gets infected a second time, memory B cells activate, quickly produce antibodies and block the virus from creating a second serious infection.
In a follow-up test, the Rockefeller scientists cloned these reserve B cells and tested their antibodies against a version of SARS-CoV-2 designed to look like one of the new variants. (The experimental virus lacked the ability to replicate, which made it safer to use in the lab.) This virus had been genetically engineered to have specific mutations in its spike protein, the part of the coronavirus that attaches to human cells. The mutations mimicked a few of the ones currently found in the variants of concern. When researchers tested the reserve cells against this mutated virus, they saw some cells produced antibodies that glommed on to the mutated spike proteins—even though these spikes were different than those on the original virus. What this means is that the antibodies had changed over time to recognize different viral features. The research was published in Nature in January. “What the paper shows us is that, in fact, the immune response is evolving—that there’s some dynamic changes over this period of time,” Nussenzweig says.
more...
Sativied
Well-Known Member
Moderna and Pfizer COVID-19 vaccines may reduce coronavirus transmission
The mRNA vaccines are about 90 percent effective at blocking coronavirus infection, which could lead to reduced transmission, real-world data suggest.
www.sciencenews.org
“Vaccines against COVID-19 are about 90 percent effective at blocking coronavirus infections, real-world studies of health care workers, firefighters, police, teachers and other essential workers suggest.”
Sativied
Well-Known Member
Ongoing trial shows Pfizer Covid-19 vaccine remains highly effective after six months
The ongoing Phase 3 clinical trial of Pfizer/BioNTech's coronavirus vaccine confirms its protection lasts at least six months after the second dose, the companies said Thursday. The trial continues and protection is expected to last longer than six months.
edition.cnn.com
Hopefully it’ll turn out to be at least a year in most cases. I’m suffering from travel withdrawal. Must be nice to live in a country where you can drive for more than 2 hours before ending up abroad or in the ocean.
Dr.Amber Trichome
Well-Known Member
That’s why I never drink Canadian.
Yande
Well-Known Member
I hear you Sativied.. Here in Australia, we have been just lucky. Nothing to do with Gov't management, (for they couldn't organise a chook raffle on a Friday night) more so, living on an island, albeit a F***ing big one. As for travel, this 7th Gen Australian is missing my annual trip to China, where I can live like the rich and famous on my beer budget. Never a popular statement, but I miss China, and if anyone thinks otherwise, well, you ain't been there, and just go believing what the MSM tells ya!
Dr.Amber Trichome
Well-Known Member
Communist China is def not in my bucket list no one could convince me otherwise.
captainmorgan
Well-Known Member
I've seen numbers quoted like 20% or more end up with long covid, the UK is admitting that over a million people have long covid.
www.theguardian.com
Almost third of UK Covid hospital patients readmitted within four months
BMJ analysis of 48,000 records also finds one in eight patients die within four months of discharge
www.theguardian.com
Dr.Amber Trichome
Well-Known Member
That’s terrible! I fell so bad for them. The suicide rate must be high.I've seen numbers quoted like 20% or more end up with long covid, the UK is admitting that over a million people have long covid.
Almost third of UK Covid hospital patients readmitted within four months
BMJ analysis of 48,000 records also finds one in eight patients die within four months of discharge
Sativied
Well-Known Member
You just made my travel withdrawal worse by mentioning Australia. I want to go back so badly, plan is next winter (your summer...) but not counting on it yet. Living on a island helps but you ozzies have more solidarity towards each other too. As soon as people here in NL figured out 90% of people on IC are either fat or immigrant they stopped caring.
Dr.Amber Trichome
Well-Known Member
My Aunt lives in Amsterdam and she is fat and rich.
Sativied
Well-Known Member
Then she should be even more careful than others.
TacoMac
Well-Known Member
This worries me.I've seen numbers quoted like 20% or more end up with long covid, the UK is admitting that over a million people have long covid.
Almost third of UK Covid hospital patients readmitted within four months
BMJ analysis of 48,000 records also finds one in eight patients die within four months of discharge
What if the longer you carry it, the more it mutates and the stronger it gets?
It's a scary thought.
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