Is CBD the Ultimate Hangover Cure? Discussion

Have you tried CBD for your hangovers?

  • Yes

    Votes: 1 16.7%
  • No

    Votes: 5 83.3%

  • Total voters
    6
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Steep Hill

Member
Sometimes there are hangovers that an indulgent breakfast and Advil can’t solve. Headaches, brain fog, nausea, dehydration, and anxiety – we’ve all been there. Enter CBD: a non-psychoactive cannabinoid known for its calming effects and ability to combat pain. Let’s explore the various ways how CBD can offer hangover relief…


CBD and Brain Fog:
The reason that we feel brain fog when we are hungover is because alcohol causes neurodegeneration. CBD, however, boasts the ability to mitigate the after-effects of alcohol on the brain by up to 50%. CBD accomplishes this by increasing brain cell production, reducing inflammation, and promoting blood flow to the brain.


CBD and Nausea:
CBD is known to have anti-emetic effects. Research suggests that this may be because of

the cannabinoid’s interaction with the brain’s serotonin receptors. For example, Zofran, a well-known anti-vomiting drug, works similarly to CBD by regulating the nauseating effects of serotonin release.


CBD and Headaches:
We get headaches the morning after a night out is because alcohol is a diuretic that causes inflammation & dehydration. CBD carries anti-inflammatory properties, similar to many over-the-counter painkillers, which help alleviate the pain naturally!


CBD and Anxiety:
CBD also helps to combat hangover anxiety. It accomplishes this by affecting serotonin levels, a neurotransmitter that plays a crucial role in mood stabilization, helps with sleep, and contributes to feelings of well-being, and happiness. Medications like anti-anxiety and antidepressants work similarly in the brain, working to regulate serotonin levels. Unlike these pharmaceuticals, CBD has fewer side effects than these medications and does not require a prescription.

Have you ever used CBD to cure a nasty hangover?
 

Steep Hill

Member
I’d love to read the study where CBD was found to increase brain cell production.
Hi drsaltzman,

I wanted to include two links for you to reference - the first is a general article that covers the benefits of using CBD for a hangover: https://boomboomcbd.com/blogs/news/cbd-for-hangover

The second link is the study itself that delves into the scientific background of this topic: https://pubmed.ncbi.nlm.nih.gov/24012796/

I hope this information interests you/answers any questions you may have :)

Best,
Steep Hill
 

drsaltzman

Well-Known Member
So it’s a reduction in neurodegeneration, not really an increase in brain cell production.
I’m just curious because if a CBD transdermal gel of 5% can diminish hangovers, consistently and reliably, that’s great.
And with some fresh marketing, I can see that selling.
But if it actually can increase production of brain cells, then that’s a whole different ballgame.
Especially if it can target more than just the entorhinal cortex.
 

Steep Hill

Member
So it’s a reduction in neurodegeneration, not really an increase in brain cell production.
I’m just curious because if a CBD transdermal gel of 5% can diminish hangovers, consistently and reliably, that’s great.
And with some fresh marketing, I can see that selling.
But if it actually can increase production of brain cells, then that’s a whole different ballgame.
Especially if it can target more than just the entorhinal cortex.
Hi Dr. Saltzman,

Interesting points! Studies are still scant and are mostly limited to in vitro and non-human mammalian studies, but there is evidence of neurogenesis for both CBD and CBG. Here are a couple of recent articles.

The role of cannabinoids in adult neurogenesis
Jack A Prenderville, Áine M Kelly, and Eric J Downer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543605/#!po=38.2653

Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-induced neurodegeneration
José Aguareles, Juan Paraíso-Luna, […]Ismael Galve-Roperh
https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/s40035-019-0148-x

Neuroprotective and Neuromodulatory Effects Induced by Cannabidiol and Cannabigerol in Rat Hypo-E22 cells and Isolated Hypothalamus Viviana di Giacomo 1, Annalisa Chiavaroli 1, Giustino Orlando 1,*, Amelia Cataldi 1, Monica Rapino 2, Valentina Di Valerio 3, Sheila Leone 1, Luigi Brunetti 1, Luigi Menghini 1 Lucia Recinella 1 and Claudio Ferrante 1

https://ricerca.unich.it/bitstream/11564/716005/1/antioxidants-09-00071 (4).pdf

We'd love to hear your thoughts! Thanks for sharing thus far :)

Best,
Steep Hill Team
 

crimsonecho

Well-Known Member
sorry for being that guy but the ultimate cure for hangovers is to stop drinking. there is no magical way to reverse what you have to your body with heavy drinking.
 
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