Operation 420
Well-Known Member
Found this and thought it would be beneficial to you guys.
Cannabis, the real medicine:
Large Study Finds No Link between Marijuana and Lung Cancer
http://www.sciam.com/article.cfm?articleID=0002491F-755F-1473-B55F83414B7F0000
Study Finds No Cancer-Marijuana Connection
http://www.washingtonpost.com/wp-dyn/content/article/2006/05/25/AR2006052501729_pf.html
Quote
The new findings "were against our expectations," said Donald Tashkin of the University of California at Los Angeles, a pulmonologist who has studied marijuana for 30 years.
"We hypothesized that there would be a positive association between marijuana use and lung cancer, and that the association would be more positive with heavier use," he said. "What we found instead was no association at all, and even a suggestion of some protective effect."
Cannabis and tobacco smoke are not equally carcinogenic. A connection between marijuana smoking and lung or colorectal cancer was not observed
http://www.harmreductionjournal.com/content/2/1/21
Quote
More people are using the cannabis plant as modern basic and clinical science reaffirms and extends its medicinal uses. Concomitantly, concern and opposition to smoked medicine has occurred, in part due to the known carcinogenic consequences of smoking tobacco. Are these reactions justified? While chemically very similar, there are fundamental differences in the pharmacological properties between cannabis and tobacco smoke. Cannabis smoke contains cannabinoids whereas tobacco smoke contains nicotine.
Furthermore, compounds found in cannabis have been shown to kill numerous cancer types including: lung cancer [9], breast and prostate [10], leukemia and lymphoma [11], glioma [12], skin cancer [13], and pheochromocytoma [14]
Por otra parte, compuestos que se encuentran en el cannabis se ha demostrado matar a numerosos tipos de cáncer, incluyendo: cáncer de pulmón [9], de mama y de próstata [10], la leucemia y el linfoma [11], glioma [12], cáncer de piel [13], y, feocromocitoma [ 14]
References:
[9]
Munson AE, Harris LS, Friedman MA, Dewey WL, Carchman RA: Antineoplastic activity of cannabinoids.
J Natl Cancer Inst 1975, 55:597-602. PubMed Abstract
[10]
Sanchez C, de Ceballos ML, del Pulgar TG, Rueda D, Corbacho C, Velasco G, Galve-Roperh I, Huffman JW, Ramon y, Cajal S, Guzman M: Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.
Cancer Res 2001, 61:5784-5789. PubMed Abstract | Publisher Full Text
[11]
McKallip RJ, Lombard C, Fisher M, Martin BR, Ryu S, Grant S, Nagarkatti PS, Nagarkatti M: Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Blood 2002, 100:627-634. PubMed Abstract | Publisher Full Text
[12]
Sanchez C, Galve-Roperh I, Canova C, Brachet P, Guzman M: Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells. FEBS Lett 1998, 436:6-10. PubMed Abstract | Publisher Full Text
[13]
Casanova ML, Blazquez C, Martinez-Palacio J, Villanueva C, Fernandez-Acenero MJ, Huffman JW, Jorcano JL, Guzman M: Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. J Clin Invest 2003, 111:43-50. PubMed Abstract | Publisher Full Text | PubMed Central Full Text
[14]
Sarker KP, Obara S, Nakata M, Kitajima I, Maruyama I: Anandamide induces apoptosis of PC-12 cells: involvement of superoxide and caspase-3. FEBS Lett 2000, 472:39-44. PubMed Abstract | Publisher Full Text
A preliminary DTI study showing no brain structural change associated with adolescent cannabis use
http://www.harmreductionjournal.com/content/3/1/17/lIDABD3EJ
Cannabis less harmful than drinking, smoking: report
http://afp.google.com/article/ALeqM5jRGC7NMbpXzbOEjhCCYVQ3my6e_w
Heavy Marijuana Use Doesnt Damage Brain
http://www.sciencenews.org/articles/20051015/fob7.asp
Quote
He and his colleagues started investigating this mystery by searching cell surfaces in live, cultured slices of rat hippocampus for receptors that respond to marijuana and a few other similar drugs, called cannabinoids. They reasoned that if marijuana affected neurogenesis in the hippocampus, then cells in that area must have a way to recognize the drug. Sure enough, 95 percent of hippocampus cells responsible for neurogenesis showed evidence of cannabinoid 1 (CB1) receptors, one of two receptors that respond to cannabinoid drugs
CB1 and CB2 receptors:
http://en.wikipedia.org/wiki/Cannabinoid_receptor
Quote
A study done on CB1 knockout mice (genetically altered mice who cannot produce CB1) showed an increase in mortality rate. They also displayed suppressed locomotor activity as well as hypoalgesa (decreased pain sensitivity). The CB1 knockout mice did respond to Delta9-Tetrahydrocannabinol. This shows that either CB2 or unknown cannabinoid receptors also have pharmacologic significance
Quote
CB2 receptors are mainly expressed on T cells of the immune system, on macrophages and B cells, and in hematopoietic cells. They also have a function in keratinocytes, and are expressed on mouse pre-implantation embryos. It is also expressed on peripheral nerve terminals. Current research suggests that these receptors play a role in nociception, or the perception of pain. In the brain, they are mainly expressed by microglial cells, where their role remains unclear.
---> Using cannabis you stimulates this cannabinoids receptors
Heart study finds benefit from pot
http://www.ocregister.com/ocr/sections/news/focus_health/article_471358.php
Marijuana Chemical Fights Hardened Arteries
http://www.webmd.com/heart-disease/news/20050406/marijuana-chemical-fights-hardened-arteries
Marijuana can prevent blindness in Glaucoma patients.
http://www.preventblindness.org/resources/factsheets/MarijuanaFS01.PDF
Marijuanas Active Ingredient Targets Deadly Brain Cancer
http://www.webmd.com/news/20000228/marijuanas-active-ingredient-targets-deadly-brain-cancer
Cannabidiol Prevents Cerebral Infarction Via a Serotonergic 5-Hydroxytryptamine1A ReceptorDependent Mechanism
http://stroke.ahajournals.org/cgi/content/abstract/36/5/1071
Cannabidiol and (−Δ9-tetrahydrocannabinol are neuroprotective antioxidants
http://www.pnas.org/cgi/content/full/95/14/8268
Neuroprotection by Delta 9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity
http://www.jneurosci.org/cgi/content/full/21/17/6475
Post-ischemic treatment with cannabidiol prevents electroencephalographic flattening, hyperlocomotion and neuronal injury in gerbils.
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=12850548&dopt=Citation
Cannabinoids and neuroprotection in CNS inflammatory disease
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T06-4G5BJYG-2&_coverDate=06/15/2005&_alid=365635784&_rdoc=1&_fmt=&_orig=search&_qd=1&_cdi=4854&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=eee6183b504cfe0f9ecd713e4c6bf29b
Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
http://brain.oxfordjournals.org/cgi/content/full/126/10/2191
Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid
http://www.letfreedomgrow.com/cmu/amyotrophic_lateral_sclerosis.htm
Decreased Depression In Cannabis Users, Study Says
http://norml.org/index.cfm?Group_ID=6586
Cannabis also protects mice against brain cell death caused by alcohol.
http://jpet.aspetjournals.org/cgi/content/abstract/314/2/780?maxtoshow=&HITS=&hits=&RESULTFORMAT=&fulltext=cannabidiol+antioxidants+diuretics+neurotoxicity&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
---> Now you know why cannabis is illegal meanwhile vaccines, fluoridated water, GMO food, and more, is legal?
Cannabis, the real medicine:
Large Study Finds No Link between Marijuana and Lung Cancer
http://www.sciam.com/article.cfm?articleID=0002491F-755F-1473-B55F83414B7F0000
Study Finds No Cancer-Marijuana Connection
http://www.washingtonpost.com/wp-dyn/content/article/2006/05/25/AR2006052501729_pf.html
Quote
The new findings "were against our expectations," said Donald Tashkin of the University of California at Los Angeles, a pulmonologist who has studied marijuana for 30 years.
"We hypothesized that there would be a positive association between marijuana use and lung cancer, and that the association would be more positive with heavier use," he said. "What we found instead was no association at all, and even a suggestion of some protective effect."
Cannabis and tobacco smoke are not equally carcinogenic. A connection between marijuana smoking and lung or colorectal cancer was not observed
http://www.harmreductionjournal.com/content/2/1/21
Quote
More people are using the cannabis plant as modern basic and clinical science reaffirms and extends its medicinal uses. Concomitantly, concern and opposition to smoked medicine has occurred, in part due to the known carcinogenic consequences of smoking tobacco. Are these reactions justified? While chemically very similar, there are fundamental differences in the pharmacological properties between cannabis and tobacco smoke. Cannabis smoke contains cannabinoids whereas tobacco smoke contains nicotine.
Furthermore, compounds found in cannabis have been shown to kill numerous cancer types including: lung cancer [9], breast and prostate [10], leukemia and lymphoma [11], glioma [12], skin cancer [13], and pheochromocytoma [14]
Por otra parte, compuestos que se encuentran en el cannabis se ha demostrado matar a numerosos tipos de cáncer, incluyendo: cáncer de pulmón [9], de mama y de próstata [10], la leucemia y el linfoma [11], glioma [12], cáncer de piel [13], y, feocromocitoma [ 14]
References:
[9]
Munson AE, Harris LS, Friedman MA, Dewey WL, Carchman RA: Antineoplastic activity of cannabinoids.
J Natl Cancer Inst 1975, 55:597-602. PubMed Abstract
[10]
Sanchez C, de Ceballos ML, del Pulgar TG, Rueda D, Corbacho C, Velasco G, Galve-Roperh I, Huffman JW, Ramon y, Cajal S, Guzman M: Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.
Cancer Res 2001, 61:5784-5789. PubMed Abstract | Publisher Full Text
[11]
McKallip RJ, Lombard C, Fisher M, Martin BR, Ryu S, Grant S, Nagarkatti PS, Nagarkatti M: Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Blood 2002, 100:627-634. PubMed Abstract | Publisher Full Text
[12]
Sanchez C, Galve-Roperh I, Canova C, Brachet P, Guzman M: Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells. FEBS Lett 1998, 436:6-10. PubMed Abstract | Publisher Full Text
[13]
Casanova ML, Blazquez C, Martinez-Palacio J, Villanueva C, Fernandez-Acenero MJ, Huffman JW, Jorcano JL, Guzman M: Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. J Clin Invest 2003, 111:43-50. PubMed Abstract | Publisher Full Text | PubMed Central Full Text
[14]
Sarker KP, Obara S, Nakata M, Kitajima I, Maruyama I: Anandamide induces apoptosis of PC-12 cells: involvement of superoxide and caspase-3. FEBS Lett 2000, 472:39-44. PubMed Abstract | Publisher Full Text
A preliminary DTI study showing no brain structural change associated with adolescent cannabis use
http://www.harmreductionjournal.com/content/3/1/17/lIDABD3EJ
Cannabis less harmful than drinking, smoking: report
http://afp.google.com/article/ALeqM5jRGC7NMbpXzbOEjhCCYVQ3my6e_w
Heavy Marijuana Use Doesnt Damage Brain
http://www.sciencenews.org/articles/20051015/fob7.asp
Quote
He and his colleagues started investigating this mystery by searching cell surfaces in live, cultured slices of rat hippocampus for receptors that respond to marijuana and a few other similar drugs, called cannabinoids. They reasoned that if marijuana affected neurogenesis in the hippocampus, then cells in that area must have a way to recognize the drug. Sure enough, 95 percent of hippocampus cells responsible for neurogenesis showed evidence of cannabinoid 1 (CB1) receptors, one of two receptors that respond to cannabinoid drugs
CB1 and CB2 receptors:
http://en.wikipedia.org/wiki/Cannabinoid_receptor
Quote
A study done on CB1 knockout mice (genetically altered mice who cannot produce CB1) showed an increase in mortality rate. They also displayed suppressed locomotor activity as well as hypoalgesa (decreased pain sensitivity). The CB1 knockout mice did respond to Delta9-Tetrahydrocannabinol. This shows that either CB2 or unknown cannabinoid receptors also have pharmacologic significance
Quote
CB2 receptors are mainly expressed on T cells of the immune system, on macrophages and B cells, and in hematopoietic cells. They also have a function in keratinocytes, and are expressed on mouse pre-implantation embryos. It is also expressed on peripheral nerve terminals. Current research suggests that these receptors play a role in nociception, or the perception of pain. In the brain, they are mainly expressed by microglial cells, where their role remains unclear.
---> Using cannabis you stimulates this cannabinoids receptors
Heart study finds benefit from pot
http://www.ocregister.com/ocr/sections/news/focus_health/article_471358.php
Marijuana Chemical Fights Hardened Arteries
http://www.webmd.com/heart-disease/news/20050406/marijuana-chemical-fights-hardened-arteries
Marijuana can prevent blindness in Glaucoma patients.
http://www.preventblindness.org/resources/factsheets/MarijuanaFS01.PDF
Marijuanas Active Ingredient Targets Deadly Brain Cancer
http://www.webmd.com/news/20000228/marijuanas-active-ingredient-targets-deadly-brain-cancer
Cannabidiol Prevents Cerebral Infarction Via a Serotonergic 5-Hydroxytryptamine1A ReceptorDependent Mechanism
http://stroke.ahajournals.org/cgi/content/abstract/36/5/1071
Cannabidiol and (−Δ9-tetrahydrocannabinol are neuroprotective antioxidants
http://www.pnas.org/cgi/content/full/95/14/8268
Neuroprotection by Delta 9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity
http://www.jneurosci.org/cgi/content/full/21/17/6475
Post-ischemic treatment with cannabidiol prevents electroencephalographic flattening, hyperlocomotion and neuronal injury in gerbils.
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=12850548&dopt=Citation
Cannabinoids and neuroprotection in CNS inflammatory disease
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T06-4G5BJYG-2&_coverDate=06/15/2005&_alid=365635784&_rdoc=1&_fmt=&_orig=search&_qd=1&_cdi=4854&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=eee6183b504cfe0f9ecd713e4c6bf29b
Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
http://brain.oxfordjournals.org/cgi/content/full/126/10/2191
Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid
http://www.letfreedomgrow.com/cmu/amyotrophic_lateral_sclerosis.htm
Decreased Depression In Cannabis Users, Study Says
http://norml.org/index.cfm?Group_ID=6586
Cannabis also protects mice against brain cell death caused by alcohol.
http://jpet.aspetjournals.org/cgi/content/abstract/314/2/780?maxtoshow=&HITS=&hits=&RESULTFORMAT=&fulltext=cannabidiol+antioxidants+diuretics+neurotoxicity&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
---> Now you know why cannabis is illegal meanwhile vaccines, fluoridated water, GMO food, and more, is legal?