but you need airflow to prevent mold/mildew. if your fan is strictly cooling your enclosed light fixture then by all means, turn it off with the lights. but your girls still need fresh air when its dark.I have my fan on the same timer as my lights, you don't necessarily need any cooling when the lights are off
then its my advise to leave it on 24/7. dont you think the air should be moving in the dark? humidity levels rise during the dark period. stale air and high humidity spell mold/mildew issues.I'm not using the fans to cool the lights, I only have 2 42 Watt CFLs and one plant, so it's not like they generate much heat or anything.
I have the fan to just move the air around in my little grow area, and to sway the stem a little to give it some more support.