Yes sir! A couple of hours before my d&r I slip it some florakleen. Direction say use 1-2 tsp ( 5-10 ml) per gallon, recirculate for 1-2 hours and drain and replenish with fresh nutes. I use 5ml per gallon when they are less that 4 weeks old and then hit them with 10 ml per gallon when they are big enough to take it and had some time to build up the extra salts I want to take out. I also use it as a final flush and add it with water only for the last couple of days per directions. Help with the res clean-up after the grow also. After a couple of days with florakleen in the tank there is a lot of gunk in the bottom of the res but the airstones are as clean as a whistle!