For my grows it was easy.. because they are smaller indoor plants (vs out door trees) and thereby easier to inspect and get every inch..
And of course I watched them daily so I caught them before it was critical infestation..
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My method for removing spider mites completely from the plant it's self is to terrorize them with simple cold water.. they HATE IT.. (often I am convinced neem is just working much the same way, drowning them, regardless of it's ablity to repel them as well)..
If you only have a few smaller plants.. take em into the shower/bath and get a spray bottle with water and drench the darn thing (it rains on buds outside too, me myself I use a blow drier set on no heat to get the water under control afterwards..
Anyway.. pure simple water.. drown their silly asses.. the plant will be dripping wet.. that is the point.. UNDER the leaves.. thats where you want to cover every inch.. just spray spray spray.. till they are drenched and dripping.. shake off water, blow em reasonably dry enough. (the whole process takes about 20 minutes once you get it down)..
While the plants are out of your closet/tent whatever, spray Raids House and Garden (about 3-4 bucks at most grocers this time of year) spray in the room and shut the door while your doing your plants.. the spray is very effective at killing all mites in the cracks and crevices yet it wont harm your plants when you put them back in,.
Do the same thing the next day..
And the next
And the next..
For a week strait.. And a week is actually over kill but you want to do overkill.
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If you have mites after that you are bringing them in from somewhere..
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I've done this up to a week before harvest.. again, just gently shake water off buds and air blow them reasonably then get them back in a warm room under lights and I haven't had any issues with mold or rot..
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Pure simple water.. mites drown easy.. you can stop damage from progressing IMMEDIATELY.. the live mites drown extremely easy..
But there will be eggs.. this is why you do it for a week in a row.. after a week you have drowned all the big guys the first day, second and third day just getting any errant ones that escaped the wrath.. and by the 4th day any hatching don't stand a chance.. after a week of this mites are either dead or have figured this environment sucks and they are out of there.
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I've done this time and time again, perfect results.. no chemicals zero.. no neem (some strains I used to have actually seemed to resent the neem once they get pocked up from mite bites.. ) which 'some say' can effect taste.
Only chemicals are the plant friendly raid house and garden spray, and I always aired out the room a few minutes before putting th plants back in,.. and it only takes a very little spray.. to fume up a small space and get into cracks and crevices and even lights and fixtures, anywhere they may be hiding out..
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Small rooms, water is all I use..
Incidentally, out doors, a garden hose comes out the mites go running, if you haven't started flowering yet it is EASY to chase mites away outside with a hose and water..
They simply hate being wet and drown incredibly easy. And will try and get the hell out and relocate if they decide it is a sucky place to try and reproduce..
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Water water water.. you can kill em dead and stop them this very day.. with simple water.. you can kill all their eggs by following up doing the same thing for a week.
After the first 2 days it is easy and quick and you hardly need any water.. the first two days, DRENCH em..
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That's my story.. take it or leave it.. it's just what I do, and the way I do it has always been 100 percent effective.. 'for me'.
Everyone else's mileage may vary.
Whatever you do, hit em as early as possible.. inspect your plants daily.. always if possible.. I never understand when people get an infestation indoors and say 'I just found them' and the plants are crawling with them.. that should never happen if you maintain them daily.. Not to be preachy or bitchy.. just check em daily even when there is no problems.. it's key to control IMO..
Hope that helps someone.. or doesn't hurt some one if they try it and they get mold or rot.. blow em mostly dry gently.. it takes some hands on.. sprays are easier.. BUT no chemicals is divine and worth the effort 'for me'.
Peace~!