Like with anyone, there are certain strains that have, or yet will, made me 'edgier' than others, but I have never had a more intense type, where's the phone because I can't deal with this and need to dial 9-H-O-L-Y S-H-I-T, type moment.
But I have seen a handful of others have very extreme, and different, reactions to getting high the first time.
The most extreme I saw was around 1973. One of my friends who always acted like he got high, but never did, one day decided he wanted to and asked if he could hang out with me. I of course said sure. It was a Saturday night without a party so a couple friends and I were just going to cruise around and get high and listen to tunes, so I figured one more person won't hurt.
I picked him up around 7:00 PM, and the other two not all that many minutes later. We drove around and got high and even though we'd all eaten, several of us, amazingly, wanted to go to McDonalds, so that's where I went.
Even before getting there my buddy, the first timer, seemed nervous. Before we got there he asked if it was a smart idea. In that era a lot of guys raced each other and McDonalds was where you'd go if you wanted to find a race. So on Friday and Saturday nights the place was really busy and there was always at least one, but usually two, local cops walking around. My friend thought it unwise for us to go that near cops. We said it was cool, sooner or later you end up doing that sort of thing all the time, so it was no big deal, don't even think about it.
I park, he won't get out of the car and doesn't want me to bring him anything because one more order would just keep us there that much longer. I said, OK.
My other friends and I are walking back to my car and my car almost looked like it had two or three people in it. My friend was moving from window to window, sides and back, so much that it seemed like there was more than just one person in the car, with a face in each window and seemingly a body almost anywhere in the car at almost any time.
My friend's and I wanted to enjoy our food but my friend really insisted that we leave, that we eat while we drive or we stop somewhere else to eat. Before I had a chance to pull out of McDonalds my friend is already coughing and telling me he doesn't feel well, that he thinks he's going to be sick.
I pulled out and then quickly pulled into a large parking lot and my buddy started spewing like Old Faithful. It seems the combination of sheer paranoia combined with the odor of burgers, it must have put him over the edge because he hadn't gotten any food, but he left his dinner in that parking lot.
In a bit I headed out again, but my friend was almost like he had been heavily drugged. He was a big rag doll that threw up. My other friend's asked me to drop them off somewhere, which I did, and then I took my friend somewhere he could relax and if not enjoy it some, at least not be almost catatonic, and sick, from fear, or some odd allergy I never heard of.
I can't set the time all that exact, but I picked him up around 7:00 PM, we were likely high by 7:40 PM, McDonalds by about 8:00PM or shortly after, dropped off my other two friends around 8:30 PM or shortly after ....... and at midnight I am wondering if just by chance while the rest of us were in McDonalds that this guy had a blood vessel break in his head, or something, because until about then he literally could walk without help and he was about as limp-bodied as if he drank a fifth or bourbon.
Once it started it only took about a half hour before he 'regained full, or near full, motor control' over himself ..... but then he was still really paranoid and would still do the dry heave thing now and then.
Friend or not, I had pretty much reached my limit, so I said I was going home, so I would drop him off at home on the way. He almost shit himself. He was positive that the instant he walked in the house his father would take one look at him and know, and he'd be in trouble. I said how it was about 12:30 AM by then and he'd be asleep so don't worry about it.
It took about 20 minutes to get to his house, and he hardly once shut up about his old man, but when we got there the house was all dark. I said everyone's asleep, walk in quietly and do what you have to as quickly and quietly as possible, and then go to bed ... and said go ... so he went.
About two years later he moved to Colorado and until he moved I never knew of him ever getting high again. He never asked me, I knew some people who offered and he turned down the offer so I'm sure for at least that long he didn't give it another try. And it's second hand, but another friend who ended up at the same college with the paranoid-pal said it's not like he really watched him and paid all that close of attention to, but he hung out with him a lot and he couldn't remember ever seeing him get high.
I really never understood what happened, but I do think that it was my friend's one and only, and absolutely miserable, time getting high.
For a few hours he was such a mess that if I had seen him at some party and I asked someone, what's up with that guy, and they said, he did a few quaaludes and then had a few shots, and some beers ......... it would have sounded completely plausible.
That might or might not seem like all that much to some, but it's the most extreme reaction I have ever seen from anyone, plus it was the guy's first time. I think it's enough to deserve a place among what would be called a rare occurrence.
For anyone thinking, era and reaction = sativa ... they'd have hit the nail on the head. We had Colombian Gold in the area a while but we got a long wave of absolutely golden, in every way, Colombian Gold (I saved and later grew a number of plants from that stuff). I am pretty sure that is what we were smoking that night.
Regardless of what it was, it didn't sit all that well with my friend. For a while he was like some guy in a cheap 'plague' movie who's 'out of it' for a few hours, and then becomes a zombie, but without the zombie changing part, just the really pathetically helpless guy that should have felt lucky that he even retained bowel and bladder control, because he lost about everything else there is to lose ... and then he came around, slowly, and to a bit, instead of the undead brain eating sort of stuff being any part of it ...... that I can remember anyway.