I lost a lot of respect or them when I found out that they often use conservative based "think tanks" for some of their information and opinions. This argument that science has been wrong and so they are wrong when we don't like their findings is a sad one. We can say that "science" thought radium was just fine for use in clock dials and in order to enhance men's sexual performance, but then they found out that it caused cancer or simply killed people outright. Does that mean that science was wrong twice? If you are basing your reality around science proving itself wrong I'll try to get you a gram or two of radium that you can paint your crotch with, after all, they were wrong about radium, so this stuff is perfectly harmless, right? The opening portion of Penn and Teller's discussion violates logic and also insults the idea of science. This sort of argument uses the short perspective of science in an effort to disprove the long view. The POINT of science is that its explanations of natural phenomenon are subject to change in order to be more accurate and as new information becomes available. This does not mean that science is fallible, it means that science works as intended. If you want a source of understanding and explanation that is ALWAYS right ALL the time from the first gitgo then I recommend you turn to religion. After all, the bible is always right, has never contradicted itself and will always remain accurate and true. (oh, I forgot, Penn is an atheist isn't he)