Advice on Pruning

First time mainlining 4 white widows.
Mid second week of flower.
Topped three times in veg.

Should I prune some of the lower branches like the one I'm pointing to? Generally, how high up should I be pruning? I'd like to get the classic mainline colas.

3x3 Gorilla Tent
3 gallon aeropots
Coco loco
Mega Crop and Sea K
Mars Hydro 2000

Leave the end and the second nodes. Trim the first node - FROM THE STEM GOING OUT.

Leave the branching.

Do this to all the shaded or interior branching.... If they got full light exposure? Leave them alone.

Thanks Doc