Building a new room ?

Tyleb173rd said:

Paint question:
Is Kilz oil based preferred for both primer and paint?

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I would indeed go with an oil-based primer, but then again I'm not averse to cleaning up with thinner rather than soap and water like a lot of people are. They give you good, reliable coverage and adhesion, and are less permeable than latex primers, which is what you appear to be looking for. I'm not sure it would really make that much difference, honestly, but the main case in support of latex primers is just that they are water-based, making cleanup simple while offering good dry times and a bit less odor.

The overall performance of oil/alkyd paints is otherwise better than latex/water-based, generally speaking. I've used regular Kilz (oil), Kilz 2 (latex/water), and some others, and they all did the job. Stain blocking over old paint or especially wood paneling is where the oil-based primers really shine but that isn't a factor with new construction and fresh sheetrock, so use whatever you're comfortable with and it will probably be perfectly forgettable. And even if you decide on oil-based primer, latex paint should be fine for you.

Painting fresh sheet rock , I find all you need is a couple of coasts of sheet rock sealer its flat white, cheap does not have any harsh fumes, if mould is going to be a problem you can use a water based bathroom flat mould resistant paint. For the floor I would use a thick vinyl helps insulate from cold easy to clean I would also roll it up 4 inches up the sheet rock after painting an seal it in. I dont like oil based paints they stink an release fumes for months, not good in my view. Happy gardening

With good air circulation paint choice doesn't matter. For a sealed room that has no vents I'd say go for the less odor/less toxic paint