I only mist the cuttings them selfs 2-3 times a day for the first 48hours. Then I just mist the dome it self 4-6 times a day until I see roots from about half of the cuttings I took.
Once half are showing a few roots out of the rapid rooter I crack the vents on the dome open half way. I have well rooted clones in 12-16 days with my big buddah cheese and g13 pineapple express.
Ive done a ton of practicing on cloning in the last four months and ive finaly have it to where in comfortable and getting 99.9% rates. If I loose one its because I tore the rapid rooter open being impatent wanting to see root development then toss it in the trash.
guess ill ad I use clonex, water with a drop of superthrive, rapid rooters, trays/domes, 4 23w 5500k cfls in a homemade hood and a 3'x2'x2' tent. The tent temps are 73-75 and inside the domes are 75-78 and 60-80% rh. I keep the plugs barely damp, I noticed when there soggy wet it slow rooting. A nice little tool to pick up for cloning is the mondi mini greenhouse hydrometer that mounts in the dome. I love mine, lets you check your enviroment without disturbing it.