Inbred strain
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Inbred strains (also called
inbred lines, or for animals
linear animals) are individuals of a particular species which are nearly identical to each other in
genotype due to long
inbreeding. Inbred strains of animals are frequently used in laboratories for experiments where for reproducibility of conclusions all the test animals should be as similar as possible. However, for some experiments, genetic diversity in the test population may be desired. Thus
outbred strains of most laboratory animals are also available.
Certain plants including the genetic
model organism Arabidopsis thaliana naturally
self pollinates, which makes it quite easy to create inbred strains in the laboratory (other plants, including important genetic models such as
Maize require transfer of
pollen from one
flower to another). For most animals, the usual procedure is mating of brother-sister pairs for 20 generations which will result in lines that are roughly 98% genetically identical. For most purposes this is sufficient to be considered an inbred strain (compare to identical twins or clones which are 100% genetically identical).
See also:
br
d
)adj.1. Produced by inbreeding.
