Thanks Whodat!
I have been keeping all options open as to what it could be and wondered about my environment. The last thing I did to them before noticing this was spray them down with some takedown spray. It's organic and I have been using it for a while without issue but I was wondering if it could have been caused by spraying them down with it during lights on.
They are sitting under a 250w MH bulb with no air circulation at the moment since my fan took a dump. I haven't had a fan in there for about a month or so though so I'm not convinced it is the lack of air circulation. I'm wondering if it could be my cat's litter box causing the problem. It sits right outside my grow room but again, it's been there for some time now without issue.