Yea you can do it... You need a cooltube. Get two 120mm fans. The cooltube is cooled by both of the 120mm fans. So one 120mm fan on left side of cabinet with 4" hole, then one 120mm fan on right side of cabinet with 4" hole. So now you have two fans on opposite sides of the cabinet, connect ducting to the left fan, run the ducting to the cooltube, than to the other right fan that draws the air out by facing it in the opposite direction. So one fan blows towards the light, while one pulls the air out.
After you do that, you then will need probably 2 more 120mm to exhaust the cab air... The two 120mm pc fans exhausting the cab can be made with a generic fish filter at walmart for your carbon filter.
Someone on another site has done this exact thing... Worked out well. However, from personal experience, 4 x 120mm fans isn't going to be cheap nor quite. You might as well just get an inline. Hope this helps, honestly, there is a reason no one uses PC fans to cool a 400. An inline connected to a carbon filter isn't as loud as you think... Unless your a kid growing in your parents house...