No, marijauna and tobacco have different amounts of chromosomes and all their genetic information is different. Firstly the two gametes from either of the plants will not join together and multiply. Then secondly, if anything did multiply or join, is would probably die early on, or be one retarded plant with no wanted properties from either of the plants ( i.e cannabinoids or nicotine or whatever in tabaco ) It would have to be done at a genetic level and would be disgustingly difficult, im not gonna say impossible but PRETTY MUCH