I leave mine on. I feel that if you miss them (I do my last defol at the end of week 2 flower), then I leave them on so that I'm not adding any stress to the plant later in bloom. I haven't done any comparisons personally, I'm still new to all this, but that is the impression I am under. I think if you plan to lollipop from the beginning and you do it correctly, it seems to be great. My buddy lollipops everything and gets some real nice colas, and all dense nice bud. I'm not sure he is harvesting more because of that though... we have the same size tent and while mine is a lot more bushy and the colas aren't quite as big, I am going to have a significant amount of weight in littles and larf... some of which looks pretty damn good too. The airy stuff I am going to wash and make bubble with. I plan on running the same clones on my next run and I am going to strip them down big time, as I want to see the difference. I have another tent going where I did no topping or training as well, just to get an idea of that too. Our outdoor plant may have less colas but the un-topped one is like twice the size, way more icy, stinks more and is far more dense... I might try not topping and just doing one big ass cola or maybe a cpl depending if the branches keep up. Sorry, I kinda went off on a tangent there... this Donny Burger is hittin right now. lol