I think any attrubutes of a person are just there naturally. Unfortunately life isn't perfect for the majority of us, and often most people's potential either gets dampened or killed off completely by conditions and circumstance.
Some people can focus better(whether its a creative endeavor, or a technical endeavor) - because they are able to cloud out the bullshit if the bullshit is taking up brain processing power. Voices in the head.
Nothing is stronger than a completely healthy mind. Unfortunately, most of us are not completely healthy in our lifestyles and end up using meds from time to time. Thats the nature of any supplement.
D.M.T. the spirit molecule was a book I looked through for a while. It covers some topics and research relative to drugs and creativity. I could be wrong, but I think if someone is able to reach a high without drugs, its better than those who smoke weed to get high. Me personally, I view my weed as a medication for bullshit that clouds my thought processes. When I feel no stress and everythings working out for me, I don't smoke weed, even when I got it.
And just like everybodys got a unique experience, everybody's got a unique chemistry.