my man.
I am dealing with this right now myself, its called downy mildew. sometimes called false mildew. Try reducing humidity to 50% or less, make sure you have space between your plants with plenty of airflow through the space, light penetrating to the lower leaves and sanitize everything in your room.. Spray with Serenade, not supernade, (but maybe that exists as well?) over the tops and bottoms of leaves, containers, and soil. Mist with plain water 24 to 48 hours later to clean leaf stomata. Keep temps in the space 76F or above as it develops at 76F and below. When misting, its best to do it right before the lights come on, and raise the lights for awhile while the mist dries. Misting before dark can help the mold grow and spread during dark, cool, moist conditions.
It shouldn't 'cripple' the entire yield, in fact your plants will have plenty of time to bounce back if you haven't begun flowering yet. The mold and the treatment will stall the plants for a second, meaning they won't grow as fast as usual while their dealing with the diesese bs, but they'll get back to it afterwards. You can use serenade up to 2 weeks before harvest and its safe for use on vegetables (meaning plants for human consumption). But the longer from harvest the better.
Best of luck. Hope this helps.