how big of a area are u controlling 4x4x6 is rough 100cf.......if u are a 8x8x6 that is 200cf........so a 400cfm fan would clear out the room 2 times a min
a 6 inch inline fan should be around 400 cfms .............if u are doing a strait ducting not many bends or to much lenght that should be more then enough
i used a 6 inch 400cfm for 2 tents .....1 had 2 600w 4 90degree bends .....other was a 1000w 2 90 degree bends with 25 feet lenght.........added a power intake of 240 cfms(6 inch booster fan with metal blades) on each tent and i was fine for more then a year of growing hydro and soil
the metal blades are better if a bug gets sucked in with a open vent odds it gets chopped instead of stunned by the plastic blades