I've tried it....and my mouth was so dry I couldnt drink enough water. My throat was all closing up from being dry. But they have preparation recipes on erowid. Because the seeds can vary greatly in potency, Youre supposed to make a tea from the seeds. The darker brown, the more potent. It tastes GOD AWFUL. We sipped ours...took about a half a mason jar apiece. But I am no expert on dosage. Try less than you think you need and drink water a lot. I think Hunter S. Thompson described being on it in one of his books as the devils weed. Its called Jimson weed or thornapple, and the seed pods don't show up on the plant till mid july, I think. Look it up for a pic.