Molecular farming - Genetic Engineering applications to increase trichome production

If i read it right it reads that trichomes are limited in storage and by diminishing the structure its contents would drip onto the leaf making it easier to harvest and thus better suited for insect repelling. The lack of structure would negate the storage problem and increase production.

It then seems to go on to say that on plants where it is not feesable to have these compounds dripping of leaves etc then it is possible by transcription to trigger the trichome to produce more or less of one particular compound and therefore increase aspects of insect repellant etc


Wagner, Walker and others/et. al have put a lot of hard study into basic structures like trichomes and compounds like anthocyanin...

....which makes you think they have a lot better weed than us!

40 years experience And I dint say I had better Just try if your successful you wont be disappointed. This method was or came around from a friend of my grand father that grew hemp for rope the process was to make bigger and stronger stems for making better rope during WW2 and indeed it did but it also made hemp produce THC

Silver Back420 said:

40 years experience And I dint say I had better Just try if your successful you wont be disappointed. This method was or came around from a friend of my grand father that grew hemp for rope the process was to make bigger and stronger stems for making better rope during WW2 and indeed it did but it also made hemp produce THC

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Silver Back420 said:

It still takes the plant but read up on Cultrazine not sure on that spelling it will increase THC levels beyond your belief.
we get about a 10% rate on germination most blogs say 1% do not grow on the plant it is poisonous! But germinate is safe seed out a plant it increase's the second year after 3rd year its time to terminate all over again but well worth the trouble's havent tried indoor yet for the plants get monstrous 12-16' range at times

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the crocus bulb stuff?? Colchicien??
if it is you are reffering to polpoidy @Sativied , @bf80255 , @homebrew420 , @homebrewer ....you guys seen this ?

edit ..
you are! that is a Gout med and will induce polyplody ... interesting stuff . do the cuttings take root??

The op's paper he pasted seems to suggest by reducing the amount of one compound via the P450 protein it would increase the amonunt of another and hence the trade off eBricktop on about where increasing one system means the others have to increase to compensate.

Although in the first part it suggests we view the trichome as a factory with the ability to produce vastly more than its limited storage capabilities allow. This would surely allow for that big increase in THC (theoretically).

2Hearts said:

The op's paper he pasted seems to suggest by reducing the amount of one compound via the P450 protein it would increase the amonunt of another and hence the trade off eBricktop on about where increasing one system means the others have to increase to compensate.

Although in the first part it suggests we view the trichome as a factory with the ability to produce vastly more than its limited storage capabilities allow. This would surely allow for that big increase in THC (theoretically).

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While all this may be true, I feel strongly that we have yet to fully harness the potential for trichome production from the unaltered plant.

2Hearts said:

The op's paper he pasted seems to suggest by reducing the amount of one compound via the P450 protein it would increase the amonunt of another and hence the trade off eBricktop on about where increasing one system means the others have to increase to compensate.

Although in the first part it suggests we view the trichome as a factory with the ability to produce vastly more than its limited storage capabilities allow. This would surely allow for that big increase in THC (theoretically).

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being that the synthesis of cbd and others to THC is a enzymic process would it stand to reason that as suggested the plant must have the "lacking uptake enzemic process" adulterated to change it to maximum thc production . NOT just add/ subtract genes it might be whole sets from known plants with high thc compared to sets from lacking to see what to switch on .... ??

Silver Back420 said:

Been going on since the 70s cutting cromizomes in plants I've read alot about it in different places but no one has achieved it like a few of us have here in Missouri to achive high THC great taste and whole buz

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Ya the good old MO I'm from Southern Missouri but I just recently moved to RI

Joedank said:

being that the synthesis of cbd and others to THC is a enzymic process would it stand to reason that as suggested the plant must have the "lacking uptake enzemic process" adulterated to change it to maximum thc production . NOT just add/ subtract genes it might be whole sets from known plants with high thc compared to sets from lacking to see what to switch on .... ??

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Read original text again, they hint that these uptake enzymatic processes are already capable of producing more and that the limiting factor was the size of the trichrome not its biosynthesis capabilities.

Joedank said:

the crocus bulb stuff?? Colchicien??
if it is you are reffering to polpoidy @Sativied , @bf80255 , @homebrew420 , @homebrewer ....you guys seen this ?

edit ..
you are! that is a Gout med and will induce polyplody ... interesting stuff . do the cuttings take root??

Click to expand...

This is all way above anybody on this forums paygrade lol

Working on a degree in that field but this is work for a PHD in Bioengineering, a staff of interns and a lot of goverment munneyz not us closet scientists.

are you referring to colchicine specifically or the OP's post? Colchicine isnt too hard to get and yes its also a gout med hahaha
"Forced chemical genetic manipulation" vs "Genetic modification" aka colchicine vs. gene modification

these 2 are pretty far seperated imo

La Cominera is supposed to be a plant somebody induced polyploidy in (supposedly via chemical manipulation) and I read they were saying it grows way better than normal MJ and produces more trichomes per Meter squared as well. but I havent looked into it or anything myself.

bf80255 said:

This is all way above anybody on this forums paygrade lol

Working on a degree in that field but this is work for a PHD in Bioengineering, a staff of interns and a lot of goverment munneyz not us closet scientists.

are you referring to colchicine specifically or the OP's post? Colchicine isnt too hard to get and yes its also a gout med hahaha
"Forced chemical genetic manipulation" vs "Genetic modification" aka colchicine vs. gene modification

these 2 are pretty far seperated imo

La Cominera is supposed to be a plant somebody induced polyploidy in (supposedly via chemical manipulation) and I read they were saying it grows way better than normal MJ and produces more trichomes per Meter squared as well. but I havent looked into it or anything myself.

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i was speaking to the OP . and the guy from missouri that has a gradfather polyploid hemp farmer really neat they were doing that "back in the day " and now he does highgrade with the same tech...
cool your in school for this!!

Joedank said:

i was speaking to the OP . and the guy from missouri that has a gradfather polyploid hemp farmer really neat they were doing that "back in the day " and now he does highgrade with the same tech...
cool your in school for this!!

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that is pretty cool.

thanks man
Biotechnologies are the future