You can sure do this, multiple strains one mother concept. The only struggle is knowing 100% which beans came from which father with more than one type of pollen flying around. Even using camel brushes, you're not going to be able to lock down "you mr pollen go here, and not here, and you other type of mr pollen stay off this branch", no I don't think so.
I'd only do this in a "no other options" scenario. If you can, put one of the boys on hold or isolate, and even pollen travels and there's no guarantee without having only 1 male.
As far as choosing and which to use, that is what makes each choice unique to the "chucker/breeder". Only you can make those decisions for you, and whatever comes from it will reflect on those choices.