I usually only prune the water leaves off( darkest green ,largest or burnt leaves) my girls just hit the 5 week mark and I trimmed then pretty good. I have a northern lights that I an using the defoliation method on right now. I'm not going to the extreme with it. I defoliated at 3 weeks after the flip and she looked pretty much naked. I did notice an increase in pistils a few days after the rapping. I will do it again every 2 weeks till harvest. She was already Lollipopped previously but so far I am seeing nothing that's hindering the production of this plant. We shall see! Your girls look so fat and juicy! Great job!