Oxycodone, why/how have you forsaken me!?

I realize this isn't hallucinatory, but please bear with me. I must get to the bottom this.

My first experience: 20mg total over 90 minutes, 3 evenly spaced oral installments, full stomach, effects exactly what you'd expect (warm, fuzzy feeling throughout, no pain, nodding).

Second experience 2.5 months later: 30mg total over 60 minutes, 3 installments: 15mg sublingual, 5mg oral 30 minutes later, 10mg insufflated minutes 30 minutes after that, empty stomach, transient fatigue 3 hours in, completely sober otherwise.

What the fuck gives? I verified they were 5mg oxycodones by their imprints and they came straight from a prescription bottle. I had taken 3mg clonazepam the night before, but that should have only intensified things if anything...

i dont know whats up with you but i must be a light weight one 10mg tab will fuck me up for a few hours. but if i take them at night they wake me up and i stay up for hours.

Thats probably a sign that your body doesnt like opiates.

it has been documented that with some pain killers like oxy contin and roxy contin that eating food will actually ENHANCE the effects of the drug. the same shit happened to me and the guy i bought them from told me about it. im sure that theres info on erowid.org

oh how i wish anything under 80 mg's of OC still got me faded... those were the days

FerretFool0x77 said:

I realize this isn't hallucinatory, but please bear with me. I must get to the bottom this.

My first experience: 20mg total over 90 minutes, 3 evenly spaced oral installments, full stomach, effects exactly what you'd expect (warm, fuzzy feeling throughout, no pain, nodding).

Second experience 2.5 months later: 30mg total over 60 minutes, 3 installments: 15mg sublingual, 5mg oral 30 minutes later, 10mg insufflated minutes 30 minutes after that, empty stomach, transient fatigue 3 hours in, completely sober otherwise.

What the fuck gives? I verified they were 5mg oxycodones by their imprints and they came straight from a prescription bottle. I had taken 3mg clonazepam the night before, but that should have only intensified things if anything...

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hmmm seems your savior is a pill. of course it will forsake you. find means of salvation else where. pills and pot/ lsd/ shrooms are toys only not gods

silasraven said:

hmmm seems your savior is a pill. of course it will forsake you. find means of salvation else where. pills and pot/ lsd/ shrooms are toys only not gods

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No, LSD and mushrooms are not gods, but calling them toys is akin to calling an 18 wheeler a plaything.

canndo said:

No, LSD and mushrooms are not gods, but calling them toys is akin to calling an 18 wheeler a plaything.

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no dobt,imho substances that can affect us like lsd/shrooms are tools to change our perception(a near priceless effect),not play things.also not something id recommend for helping everyone like cannabis has the potential to.

Heu bra, U must not b getting what u wanted ??? I live on the Sht.. What u need 2 do is take more at first because if u nickle n dime it its a waste !!! It only takes 30 min. 2 feel it & if u do whats written u waste it, so if u dont feel it after 30min. to n hr. take more then u will feel it but dont wait hrs. 2 take more, thats a waste !!! Take them on n empty stomach n it works better, but it sounds like ur not getting what u paid 4 !!!

penguinking said:

it has been documented that with some pain killers like oxy contin and roxy contin that eating food will actually ENHANCE the effects of the drug. the same shit happened to me and the guy i bought them from told me about it. im sure that theres info on erowid.org

Click to expand...

It actually doesn't do shit for oxycodone. It's only been observed with oxymorphone, and it works by increasing the absorption which increases bioavailability. Seeing as oxycodone has an amazingly high oral bioavailability (as high as 87% in one study) this can't really do anything. Oxymorphone on the other hand has an oral bioavailability of about 10% so there is plenty of extra drug to absorb. If this was going to work with other opiates or semisynthetics it would be the other morphones/morphine derivatives. That methoxy group at the 3 position changes opioid activity a lot.

To the OP space your doses less and don't try to sub opioids that aren't designed for it. They don't work well that way, and condones have awesome bioavailability. Really no reason to take them any other way, unless you're getting them as pure powders.