South African scientist thinks she may have solved the mystery of long COVID-19, which afflicts 100 million people
A scientist in South Africa believes she and her colleagues have found a critical clue in solving the mystery of long COVID: microclots.
“A recent study in my lab revealed that there is significant microclot formation in the blood of both acute COVID-19 and long COVID patients,” Resia Pretorius, head of the science department at Stellenbosch University in South Africa,
wrote Wednesday in an op-ed.
Pretorius writes that healthy bodies are typically able to efficiently break down blood clots through a process called fibrinolysis. But, when looking at blood from long COVID patients, “persistent microclots are resistant to the body’s own fibrinolytic processes.”
Pretorius’ team in an
analysis over the summer found high levels of inflammatory molecules “trapped” in the persistent microclots observed in long COVID patients, which may be preventing the breakdown of clots.
Because of that, cells in the body’s tissues may not be getting enough oxygen to sustain regular bodily functions, a condition known as cellular hypoxia.
“Widespread hypoxia may be central to the numerous reported debilitating symptoms” of long COVID, Pretorius writes.
Symptoms of long COVID vary between cases, but primarily include fatigue, brain fog, muscle or joint pain, shortness of breath, sleep difficulties, and depression or anxiety.
The Department of Health and Human Services in June
released new guidance in which some symptoms of long COVID could qualify as a disability under the Americans with Disabilities Act.
In December, the Equal Employment Opportunity Commission
issued an update to its own guidance, which now considers an individual who has contracted COVID-19 disabled if any of their symptoms “substantially limits one or more major life activities.”
A recent study by Resia Pretorius and her team at Stellenbosch University in South Africa suggests that long COVID-19 may be triggered by microclots.
thehill.com