Obviously science should be the driver that shapes a grow system, whether based on synthetics or organic inputs or both. I remember when hydroponics was a "church", and people paid big dollars to many snake oil salesmen for membership. Back in the late 80s, early 90s, it was a popular thought that you couldn't produce anything of quality growing any other way except by hydro. Any good bud was often called "hydro" regardless if it was grown that way or not. It's organic's turn now. Money always finds a way! lol
For organic "soil" growers, I would exercise caution however when adding salts to your soil. That means getting a complete soil analysis and nitrogen management report from an accredited lab before deciding if, what, and how much to add. If you consistently add even a bit more than the plant can use up before the next feeding, you'll get an imbalance that could lead to toxicity or lockout conditions which will adversely affect your soil life and kill your plants. Soil is not hydro where we have full control over the nutrient levels available to the plant at all times. Adding a synthetic nute solution called "Ultra Hugely Bud Enhancer" or whatever the salesman might call it in an amount "guessed" by the grower is foolish.
What limits microbial mass in field soil is most often carbon, not N, P, or K (since they add that). Farmers for generations now have been applying nitrates or urea to the soil (which bacteria love), however the carbon they need to take advantage of it becomes less available as bacteria populations explode shortly after application, since their respiration removes the last remnants of carbon from the soil in the form of CO2. The loss in soil carbon contributes to a corresponding loss in soil tilth, lowers CEC, as well as microbial mass over the long term. Even with a soil test, I would advise those who want to use synthetics to insure they always have enough digestible carbon to achieve a reasonable C:N ratio. For those doing no-till, I'd avoid salts completely unless you had a dire emergency (confirmed by a soil test).