If you want big yields you will get more out of a true F1 (meaning regular seed). I think there are some interesting smaller regular breeders, my experience with Think Different left a poor taste in my mouth. I had one die due to genetics early (recessive lethal, cause I sure as shit didn't do anything to kill it and it had no bugs) after it sprouted it died (this happens, many folks don't know but it is a result of inbreeding, if you breed with your cousin there's a 1/8 chance you'll find a lethal recessive trait you both share in your offspring, something like that, not all being created equally).
I just wrote a lengthy write up on the TD, another one said to be a good producer and overall my impression is not all that favorable. It's not total garbage, but man, except one plant, it's not impressive at all either (quality wise and even that nice plant isn't exactly overwhelmingly strong like some regular strains). Some of em yielded pretty heavy but the bud structure was horrible. Depends on what your goals are.
I think if I ran an auto again it would be from stitch or those guys who do Onyx (I tihnk it's called). I might give Spyder a try too, I am liking it's genetic heritage and the guy who bred it seems to know what he's doing. Its on attitude. It's also a regular seed so it should have more vigor.