Neem oil can leave a taste so I wouldn't if possible. I used an aerosol low value pyrethrum last year and it worked quite well on the spider mites in my green house and they were about 4 weeks into flower. Use it twice so you get the eggs too. This year, I got spider mites on my indoor a few days before harvest so I just pulled the plants and washed them off with water, let 'em dry for a day out in the sun and then lights off and harvest. That worked very well but I was AT harvest and wasn't going to put anything on the buds other than water. I can say that I was surprised how well the spider mites washed off the plant. I've already got my next soil cooking and it contains both neem and karanja cake and I'm hoping that really helps keep the pests at bay. Guess, I'll know in a few months. I also have neem oil and will be spraying prophylactically during veg on the next grow. These pests are really a pain once they appear. I'm hoping to keep things more at bay in the future.