This is the formula for ambient capture of VOC and particulate. You seem to be conflating with resistance and static fan pressure which usually apply to source capture - such as losses because of runs of ducting, bends, etc. The short piece of duct that most novice growers here use won't really cause anything in the way of losses in inches of water column.
You are also mixing in HVAC and lighting temps which are a separate thing entirely from sizing a fan/carbon filter and how to calculate ACPH.
Who exhaust soley for smell control without ever taking environment into consideration? If you size your carbon filter and fan without taking into consideration the heat load being produced in the room you will be undersized and unable to deal with the heat load.
The only way I could see your calculation working is in a totally sealed room with a mini split and c02 enrichment. I run that way in one room now (but don't vent when doing so), but the majority of people on here run tents or small rooms and exhaust to control environment.
Not trying to be insulting I think it's just lack of experience in setting up grow rooms. But you kinda remind me of some HVAC tradesmen I've tried to get estimates from. They try their standard calculations and try to tell me some stupid low number of btu for my grow room. They fail to account for the amount of heat produced by lamps and other heat producing devices in the room, and even if they do try to calculate a heat load it still comes up low. I end up having to just find people that will let me size my own equipment or do it my self. So far I've been spot on with my calculations that I got from formulas I found on places like this vs the way off calculations that come from the hvac industry.
I really don't think this is even what the OP meant, I think he simply wanted to know if too much negative pressure was effecting his plants in a negative way. I say possibly, but I ran with high negative pressure for years and I think the benefits outweigh a few wind burned leaves. If it's a really high negative pressure you can always turn the fan down some with a speed controller, but I feel keeping some negative pressure is beneficial.