Driven down Lombard, and up to Qoit Tower? The tower is nice at night.
When I take friends to the city (it's where I grew up) I start on a street car by the zoo, the end of the line (it's a good zoo)... all the way to Market, then swap over to a cable car... China Town, Ghirardelli Square (the best ice cream in the world), and Fisherman's Wharf await!!
Then, after returning the same way, hop in the car and drive to the beach (you are right there at the zoo) Cliff House, through the park...The Japanese Tea Garden and Steinhart Aquarium are great. Then continue to Lombard Street and up to Qoit Tower. That is really more two days as the whole streetcar ride is a day itself.
How much time do you have? That is the "hurry up" version. But you get to see a good amount of the city by using the street car, and one of my favorites, through the Portal Tunnel (used to jump on the back and ride through the tunnel when I was a kid) and through some neighborhoods
There is a lot more, that's just what works for me when I take someone that has never been.