Anytime after about 2-4 weeks, depending on the overall health and vigor of the plant(s). If the plant or plants are healthy and growing, you may find it best to start at only about half the recommended dosage for the first feeding or two, then gradually work up to full stregth. Do not try to treat any plants that appear unhealthy before giving any nutes, BY giving nutes. That just means the initial conditions are not favorable, and force-feeding an already unhealthy plant will most likely only worsen the condition. If your babies are about 8-10 inches and at least two weeks or so old, and appear healthy and vibrant, you can start giving them their "vitamins"to promote healthy, strong growth.