Will You Take The Vaccine?

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DIY-HP-LED

Well-Known Member

COVID-19 survivors are twice as likely to get re-infected, are urged to get vaccinated
Vaccinated survivors can make antibodies that can recognize all kinds of variants even if you were never exposed to the variant.

Even people who have recovered from COVID-19 are urged to get vaccinated, especially as the extra-contagious delta variant surges — and a new study shows survivors who ignored that advice were more than twice as likely to get reinfected.

Friday’s report from the Centers for Disease Control and Prevention adds to growing laboratory evidence that people who had one bout of COVID-19 get a dramatic boost in virus-fighting immune cells — and a bonus of broader protection against new mutants — when they’re vaccinated.

“If you have had COVID-19 before, please still get vaccinated,” said CDC Director Dr Rochelle Walensky. “Getting the vaccine is the best way to protect yourself and others around you, especially as the more contagious delta variant spreads around the country.”

According to a new Gallup survey, one of the main reasons Americans cite for not planning to get vaccinated is the belief that they’re protected since they already had COVID-19 . From the beginning health authorities have urged survivors to get the broader protection vaccination promises. While the shots aren’t perfect, they are providing strong protection against hospitalization and death even from the delta mutant.

Scientists say infection does generally leave survivors protected against a serious reinfection at least with a similar version of the virus, but blood tests have signaled that protection drops against worrisome variants.

Researchers studied Kentucky residents with a lab-confirmed coronavirus infection in 2020, the vast majority of them between October and December. They compared 246 people who got reinfected in May or June of this year with 492 similar survivors who stayed healthy. The survivors who never got vaccinated had a significantly higher risk of reinfection than those who were fully vaccinated, even though most had their first bout of COVID-19 just six to nine months ago.

A different variant of the coronavirus caused most illnesses in 2020, while the newer alpha version was predominant in Kentucky in May and June, said study lead author Alyson Cavanaugh, a CDC disease detective working with that state’s health department.

That suggests natural immunity from earlier infection isn’t as strong as the boost those people can get from vaccination while the virus evolves, she said.

There’s little information yet on reinfections with the newer delta variant. But U.S. health officials point to early data from Britain that the reinfection risk appears greater with delta than with the once-common alpha variant, once people are six months past their prior infection.

“There’s no doubt” that vaccinating a COVID-19 survivor enhances both the amount and breadth of immunity “so that you cover not only the original (virus) but the variants,” Dr Anthony Fauci, the US government’s top infectious disease expert, said at a recent White House briefing.

The CDC recommends full vaccination, meaning both doses of two-dose vaccines, for everyone.

But in a separate study published Friday in JAMA Network Open, Rush University researchers reported just one vaccine dose gives the previously infected a dramatic boost in virus-fighting immune cells, more than people who have never been infected get from two shots.

Other recent studies published in Science and Nature show the combination of a prior infection and vaccination also broadens the strength of people’s immunity against a changing virus. It’s what virologist Shane Crotty of California’s La Jolla Institute for Immunology calls “hybrid immunity.”

Vaccinated survivors “can make antibodies that can recognize all kinds of variants even if you were never exposed to the variant,” Crotty said. “It’s pretty sweet.”

One warning for anyone thinking of skipping vaccination if they had a prior infection: The amount of natural immunity can vary from person to person, possibly depending on how sick they were to begin with. The Rush University study found four of 29 previously infected people had no detectable antibodies before they were vaccinated — and the vaccines worked for them just like they work for people who never had COVID-19 .

Why do many of the previously infected have such a robust response to vaccination? It has to do with how the immune system develops multiple layers of protection.

After either vaccination or infection, the body develops antibodies that can fend off the coronavirus the next time it tries to invade. Those naturally wane over time. If an infection sneaks past them, T cells help prevent serious illness by killing virus-infected cells -- and memory B cells jump into action to make lots of new antibodies.

Those memory B cells don’t just make copies of the original antibodies. In immune system boot camps called germinal centers, they also mutate antibody-producing genes to test out a range of those virus fighters, explained University of Pennsylvania immunologist John Wherry.

The result is essentially a library of antibody recipes that the body can choose from after future exposures — and that process is stronger when vaccination triggers the immune system’s original memory of fighting the actual virus.

With the delta variant’s super infectiousness, getting vaccinated despite a prior infection “is more important now than it was before to be sure,” Crotty said. “The breadth of your antibodies and potency against variants is going to be far better than what you have right now.”
 

DIY-HP-LED

Well-Known Member
Delta variant drives COVID-19 surge in U.S., pushes some toward vaccines

The delta variant has driven COVID-19 cases in the U.S. back up to more than 100,000 a day. And while officials warn of a coming jump in hospitalizations and deaths, there are signs that some people who were previously reluctant have signed up for a vaccine.
 

DIY-HP-LED

Well-Known Member

Unvaccinated adults are bringing Covid home to their kids. Pediatricians are overwhelmed.

As vaccination rates lag and the new delta variant surges, Covid infection rates among kids have risen and children’s hospitals are seeing a spike in medical care needs among the young patients.

The Covid surge is also stacking upon an unseasonable spike in respiratory illnesses among children typically seen only in winter. That has shrunk the bed space further in children's hospitals and expanded on the unrelenting demand on doctors and nurses.

“It is scary, especially for kids who don’t fully understand what’s going on. They’re air hungry, struggling for breath, and it’s just scary,” said Dr. Kelechi Iheagwara, medical director of the pediatric intensive care unit at the Our Lady of the Lake Children’s Hospital in Baton Rouge, Louisiana. “You have the illness, the fear, they can’t breathe, they’re isolated — that’s hard for anyone to understand, but can you imagine what it’s like for a kid?”

Her hospital has treated Covid in children ages from 3-week-olds to 17-year-olds in recent weeks. Iheagawara said that for the past month, her unit has had to treat 25 or 26 patients in a space designed for 20. And things are getting worse.

Multiple doctors in the half-dozen children’s hospitals NBC News reached out to said they have seen children infected because a member of their household, often a parent, brings the coronavirus home. Oftentimes, it is because an adult in the home is unvaccinated.

“Absolutely, household infections are the beginning of this pandemic, that is a major driving force in the spread of infections. We see it often within households, parents to children,” said Dr. Jim Versalovic, the chief pathologist and interim chief pediatrician at Texas Children’s Hospital in Houston. “We have certainly seen siblings — more than two at times — with an infection at the same time, so spread within households is certainly a very real phenomenon.”

The Covid-19 spike hit the Baton Rouge children's hospital in mid-July and brought its monthly total to 75 cases — the highest number of coronavirus hospitalizations during the entire pandemic. With 27 children admitted to the emergency room over the first four days of August, the hospital has already seen more child hospitalizations than it saw in the entire month of June.
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HGCC

Well-Known Member
Met some parents who enrolled their kids in the trials to roll this out to kids at this back to school picnic. Encouraging and discouraging, based on what they said it sounds like the next group might be a wider age range but will not get here that quickly. I think they had a 5 and an 8 year old. Pretty interesting to hear about.
 

printer

Well-Known Member
Pentagon to require all troops to get coronavirus vaccine by mid-September
The Pentagon will require all military personnel to get the COVID-19 vaccine by Sept. 15 or sooner, according to a new memo from Defense Secretary Lloyd Austin, released Monday.

“I will seek the president’s approval to make the vaccines mandatory no later than mid-September, or immediately upon” final approval by the Food and Drug Administration (FDA) “whichever comes first,” Austin wrote in the memo to troops.

If infection rates rise and potentially affect military readiness, “I will not hesitate to act sooner or recommend a different course to the President if l feel the need to do so. To defend this Nation, we need a healthy and ready force,” Austin added.

“Secretary Austin and I share an unshakable commitment to making sure our troops have every tool they need to do their jobs as safely as possible,” Biden said in a statement.

“Being vaccinated will enable our service members to stay healthy, to better protect their families, and to ensure that our force is ready to operate anywhere in the world. We cannot let up in the fight against COVID-19, especially with the Delta variant spreading rapidly through unvaccinated populations. We are still on a wartime footing, and every American who is eligible should take immediate steps to get vaccinated right away.”

The Pentagon now adds the coronavirus vaccine to the list of more than a dozen shots it requires service members to get, including shots for measles, mumps, diphtheria, hepatitis, smallpox and the flu.
 

DIY-HP-LED

Well-Known Member
The vaccines are spectacularly successful, even in dealing with the delta variant, they prevent serious illness and death very well, for the older strains of covid it even prevents transmission. The new super contagious delta variant does cause breakthrough infections in the vaccinated mostly producing asymptomatic or mild cases of the "Wu Flu".
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Less Than 0.01 Percent of Vaccinated Americans Developed Severe COVID Breakthrough Case, CDC Says

According to the latest data released by the CDC, less than 0.01 percent of vaccinated individuals have developed COVID breakthrough infections resulting in serious health complications or death.

As of August 2, more than 164 million people have been fully inoculated against the disease, CDC numbers indicate. Less than 0.001 percent of this population have suffered severe or fatal cases of COVID when they contracted it post-vaccination. Since the vaccine’s distribution, the agency has received reports of 7,525 patients with COVID-19 vaccine breakthrough infections who were hospitalized or died.

“Vaccine breakthrough cases are expected. COVID-19 vaccines are effective and are a critical tool to bring the pandemic under control. However, no vaccines are 100% effective at preventing illness in vaccinated people. There will be a small percentage of fully vaccinated people who still get sick, are hospitalized, or die from COVID-19,” the CDC wrote.


People aged 65 or older experienced the bulk, about 74 percent, of the reported severe breakthrough infections. About 21 percent of the approximately 1,500 people who died after contracting COVID after vaccination were reported as asymptomatic or not related to COVID, the CDC confirmed.

Currently, the CDC uses the REDCap database to report cases, “where designated state health department investigators can enter, store, and manage data for cases in their jurisdiction.” In the future, the CDC plans to transition to the National Notifiable Diseases Surveillance System (NNDSS) to account for vaccine breakthrough cases.

Since May, the CDC has only been monitoring hospitalized or fatal cases rather than all vaccine breakthrough cases. “This shift will help maximize the quality of the data collected on cases of greatest clinical and public health importance,” the organization said.

While 10,262 total vaccine breakthrough infections were reported to the CDC from 46 U.S. states and territories as of April 30, 2021, still only a fraction of these cases proved to be life-threatening or reason to seek emergency medical attention. Nearly 3,000 of these vaccine breakthrough infections were asymptomatic, 995 resulted in hospitalization, and 160 resulted in death.
 

DIY-HP-LED

Well-Known Member
Dr. Fauci: There's No Doubt These Vaccines Will Be Fully-Approved By FDA

Director of National Institute of Allergy and Infectious Diseases, Dr. Anthony Fauci, discusses areas of the U.S. being ravaged by the coronavirus and why Americans should consider the vaccine as good as fully-approved by the FDA.
 

DIY-HP-LED

Well-Known Member
70% of the resistant eligible unvaccinated are republicans.
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Politics Expert Says Of GOP COVID Deniers ‘The Republican Party Only Cares About ME’

The COVID-19 virus has mutated into the super-contagious delta variant, leading to pandemic surges nationwide. As Republican leaders such as Florida Gov. Ron DeSantis and Texas Gov. Greg Abbott make choices for their states that will make it more difficult to battle the pandemic, Joy Reid and her guests critique the widespread conservative push to demonize vaccine and mask mandates.
 

printer

Well-Known Member
Twitter temporarily suspends Greene after she says vaccines are 'failing'
A Twitter spokesperson told The Hill in a statement that her tweet on Monday “was labeled in line with our COVID-19 misleading information policy.”

Her account will be in read-only mode for one week “due to repeated violations of Twitter Rules,” the spokesperson added.

Greene said in the tweet that the Food and Drug Administration (FDA) "should not approve the covid vaccines."

"There are too many reports of infection & spread of #COVID19 among vaccinated people," Greene said.

"These vaccines are failing and do not reduce the spread of the virus & neither do masks," she added. "Vaccine mandates & passports violate individual freedoms."
 

captainmorgan

Well-Known Member

DIY-HP-LED

Well-Known Member
It's been rare the onion has been weirder than reality lately, Trump often topped them for the absurd and the republicans are doing a pretty good job of stupid lately too. Their base is literally dying to own the libs and guys like Paul are fucking nuts, the story could have just as easily run in the NY times, from what I've seen of the lunacy of republicans.
 

DIY-HP-LED

Well-Known Member

Excerpt:
"Many of Arkansas Children’s new COVID-19 patients are also much more ill than before. They’re coming in with wrecked lungs, struggling to breathe; they’re not bouncing back with typical youthful resilience, despite having been very healthy before. “This COVID surge, I’ve never seen anything like it,” Linda Young, a respiratory therapist who’s been on the job for 37 years, told me. “It’s the sickest I’ve ever seen children.” It’s become common for more than half of the kids in the ICU to be on ventilators. A few have been in the hospital for more than a month. “We are not able to discharge them as fast as they are coming,” Abdallah Dalabih, a pediatric critical-care physician, told me. Some parents, Snowden said, are in disbelief. “Many people didn’t believe kids could get this thing,” she said".
 

DIY-HP-LED

Well-Known Member
My first shot was a Pfizer and about 3 weeks ago I got a Moderna as the second jab, if this study holds true, I'm glad I did!

Real world data indicates that both of these vaccines protect against hospitalizations and death from delta, but not so much against getting mildly sick and contagious
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New data on coronavirus vaccine effectiveness may be "a wakeup call"
https://www.axios.com/authors/caitlin/
A new preprint study that raises concerns about the mRNA vaccines' effectiveness against Delta — particularly Pfizer's — has already grabbed the attention of top Biden administration officials.
What they're saying: The study found the Pfizer vaccine was only 42% effective against infection in July, when the Delta variant was dominant. "If that's not a wakeup call, I don't know what is," a senior Biden official told Axios.
Driving the news: The study, conducted by nference and the Mayo Clinic, compared the effectiveness of the Pfizer and Moderna vaccines in the Mayo Clinic Health System over time from January to July.
  • Overall, it found that the Moderna vaccine was 86% effective against infection over the study period, and Pfizer's was 76%. Moderna's vaccine was 92% effective against hospitalization and Pfizer's was 85%.
  • But the vaccines' effectiveness against infection dropped sharply in July, when the Delta variant's prevalence in Minnesota had risen to over 70%.
  • Moderna was 76% effective against infection, and Pfizer was only 42% effective.
  • The study found similar results in other states. For example, in Florida, the risk of infection in July for people fully vaccinated with Moderna was about 60% lower than for people fully vaccinated with Pfizer.
Why it matters: Although it has yet to be peer-reviewed, the study raises serious questions about both vaccines' long-term effectiveness, particularly Pfizer's.
  • It's unclear whether the results signify a reduction in effectiveness over time, a reduced effectiveness against Delta, or a combination of both.
  • “Based on the data that we have so far, it is a combination of both factors," said Venky Soundararajan, a lead author of the study. "The Moderna vaccine is likely — very likely — more effective than the Pfizer vaccine in areas where Delta is the dominant strain, and the Pfizer vaccine appears to have a lower durability of effectiveness.”
  • He added that his team is working on a follow-up study that will try to differentiate between the durability of the two vaccines and their effectiveness against Delta.
Yes, but: There has been no data so far that has found either vaccine's protection against severe disease and death is significantly less against Delta, and the study notes that there doesn't appear to be much of a difference in complications stemming from breakthrough infections based on which vaccine someone got.
  • And experts cautioned against rushing to conclusions.
  • “This is the kind of surprising finding that needs confirmation before we should accept its validity," said Cornell virologist John Moore.
Between the lines: The two shots both use mRNA, but there are significant differences between them.
  • For example, Moderna is given in a stronger dose than Pfizer, and there is a slightly different time interval between shots.
  • "There are a few differences between what are known to be similar vaccines .... None of these variables is an obvious smoking gun, although the dosing amount seems the most likely to be a factor," Moore said.
In a statement, Pfizer said it and BioNTech "expect to be able to develop and produce a tailor-made vaccine against that variant in approximately 100 days after a decision to do so, subject to regulatory approval."
Editor's note: This story has been updated to include a statement from Pfizer.
 
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